Results 71 to 80 of about 73,973 (286)

The Microbiota Shapes Central Nervous System Myelination in Early Life

open access: yesAdvanced Science, EarlyView.
Gut microbiota shapes brain development by regulating myelination and glial cell maturation in early life. Using germ‐free (GF) mice and zebrafish, this study reveals sex‐ and age‐dependent effects on myelin growth, integrity, and related gene expression.
Caoimhe M. K. Lynch   +13 more
wiley   +1 more source

Stimuli‐Responsive Supramolecular Biomaterials for Cancer Theranostics

open access: yesAdvanced Science, EarlyView.
The ultimate goal of cancer theranostics is to get imaging agents and therapeutic cargo to tumor sites when and where they are required. “Smart” systems should be developed. This review discusses the characteristics of physiological stimuli, types and action modes of external stimuli, construction approaches and working principles, as well as ...
Wenting Hu   +4 more
wiley   +1 more source

Exploring viewpoint in The Tempest: exemplification level 5 (Active Shakespeare: Capturing evidence of learning) [PDF]

open access: yes, 2010
Part of the 'Active Shakespeare: Capturing evidence of learning' suite of resources. "What is it about Providing active and engaging ways to integrate Shakespeare in the ongoing periodic assessment of pupils’ reading. What is it for?

core  

Undergraduate Research Journal, Volume 14 [PDF]

open access: yes, 2015
Table of Contents: The Myth of Chechen Radical Islam / by Jonathan Parker (p.1-8) -- Genre and the Perception of Massacre... / by Lauren Ferguson (p.9-18) -- Sentinel of Liberty: Captain America on the Home Front in WWII / by Carolyn McNamara (p.19-34) --
Ferguson, Lauren   +8 more
core   +1 more source

Caspase‐3/GSDME‐Mediated Trophoblast Pyroptosis and Reciprocal Macrophage Polarization Contribute to Inflammation in Early‐Onset Preeclampsia

open access: yesAdvanced Science, EarlyView.
In trophoblast cells, T/S (TNFα + SM164) activated caspase‐3, which cleaved GSDME to switch apoptosis to pyroptosis, causing cell swelling, membrane rupture, and release of LDH, HMGB1, IL‐1β and IL‐18. These cytokines induced pro‐inflammatory macrophage polarization, which in turn reinforced pyroptotic signaling in trophoblasts, amplifying systemic ...
Baoying Huang   +15 more
wiley   +1 more source

Absorption of sound in air below 1000 cps [PDF]

open access: yes
Absorption of sound in air measured for varying conditions of pressure, temperature, and ...
Harris, C. M., Tempest, W.
core   +1 more source

Targeted Extracellular Vesicles Deliver Asiaticoside to Inhibit AURKB/DRP1‐Mediated Mitochondrial Fission and Attenuate Hypertrophic Scar Formation

open access: yesAdvanced Science, EarlyView.
Hypertrophic scar formation is driven by excessive mitochondrial fission in wound macrophages, which we discover is governed by a novel AURKB‐DRP1(Ser616) axis. The study develops a targeted therapy using cRGD‐decorated extracellular vesicles to deliver the natural compound Asiaticoside specifically to macrophages.
Luyu Li   +8 more
wiley   +1 more source

Faculty Concert: The Tempest Trio, December 7, 2001 [PDF]

open access: yes, 2001
This is the concert program of the Tempest Trio performance on Friday, December 7, 2001 at 8:00 p.m., at the Tsai Performance Center, 685 Commonwealth Avenue. Works performed were Piano Trio in B-flat Major, Op.
School of Music, Boston University
core  

An analysis of the environment and competitive dynamics of management research [PDF]

open access: yes, 2009
Purpose – The purpose of this paper examines some of the controversies facing business schools in their future evolution and pays particular attention to their competitive positioning as centres of management research.
Alex Wilson, Eric Cornuel, Howard Thomas
core   +2 more sources

Depletion of the RNA‐Editing Enzyme ADAR1 Invigorates the Antitumor Immunity of NK Cells

open access: yesAdvanced Science, EarlyView.
ADAR1 is upregulated in NK cells from melanoma patients, impairing their function. Its loss enhances NK cell tumor infiltration and cytotoxicity in vitro and in vivo. Mechanistically, ADAR1 deficiency destabilizes CD38 mRNA to reduce its expression, thereby increasing NK cell mobility and killing, which nominates it as a therapeutic target for NK cell ...
Shuhan Chen   +11 more
wiley   +1 more source

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