Results 41 to 50 of about 951,913 (317)

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Images recognition by template matching depended on correlation coefficient [PDF]

مجلة التربية والعلم, 2010
In this research it has been using template matching to images recognition, after saving some templates for images as like geometrical shapes English characters and numbers and then input the template which is to be recognized after normalizing it to ...
hadeya Salih Abdullah
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Formulir Berlangganan, Template, Pedoman Penulisan

, 2018
Formulir Berlangganan, Template, Pedoman ...
Pedoman Penulisan, Formulir Berlangganan, Template,
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

MEL documentation template for innovations

, 2022
The template provides various sections that permit to record innovations in the Monitoring, Evaluation and Learning (MEL) Platform, WIPO Green Database, Global Innovation Exchange Platform and Rural Solution Portal but also it permits to track the ...
Clarke, Victoria
core  

Substitution effect and effect of axle’s flexibility at (pseudo-)rotaxanes

Beilstein Journal of Organic Chemistry, 2014
This study investigates the effect of substitution with different functional groups and of molecular flexibility by changing within the axle from a single C–C bond to a double C=C bond.
Friedrich Malberg, Jan Gerit Brandenburg, Werner Reckien, Oldamur Hollóczki, Stefan Grimme, Barbara Kirchner   +5 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Templates for Binary Matroids [PDF]

SIAM Journal on Discrete Mathematics, 2017
A binary frame template is a device for creating binary matroids from graphic or cographic matroids. Such matroids are said to conform or coconform to the template. We introduce a preorder on these templates and determine the nontrivial templates that are minimal with respect to this order.
Kevin Grace 0001, Stefan H. M. van Zwam
openaire   +4 more sources

Surface Topography-Based Positioning Accuracy of Maxillary Templates Fabricated by the CAD/CAM Technique for Orthognathic Surgery without an Intermediate Splint

Applied Sciences, 2019
Computer-aided design/computer-aided manufacturing (CAD/CAM)-based maxillary templates can transfer a surgical plan accurately only when the template is positioned correctly.
Jeong Joon Han, Soon Jung Hwang
doaj   +1 more source