Results 71 to 80 of about 1,043,977 (317)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Host–guest chemistry of mesoporous silicas: precise design of location, density and orientation of molecular guests in mesopores

open access: yesScience and Technology of Advanced Materials, 2015
Mesoporous solids, which were prepared from inorganic-surfactant mesostructured materials, have been investigated due to their very large surface area and high porosity, pore size uniformity and variation, periodic pore arrangement and possible pore ...
Minoru Sohmiya   +2 more
doaj   +1 more source

Effects of Different Templates on Electrochemical Performance of LiFePO4/C Prepared by Supercritical Hydrothermal Method

open access: yesInternational Journal of Electrochemical Science, 2016
In this study, LiFePO4/C has been synthesized by supercritical-hydrothermal method followed with solid phase calcination using three different templates; hexadecyl trimethyl ammonium bromide (CTAB), sucrose and polyvinyl pyrrolidone (PVP). The effects of
Xuewu Liu   +3 more
doaj   +1 more source

Template

open access: yes, 2010
Template for Author ...
Author Guideline, Template for
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Design and application of a novel 3D printing digital navigation template for cubitus varus deformity in children

open access: yesFrontiers in Pediatrics
BackgroundThis study was aimed to assess the feasibility and efficacy of 3D printing digital template for treatment of cubitus varus deformity.Methods32 patients who underwent lateral closing osteotomy were evaluated between January 2018 and January 2020
Ming Zou   +4 more
doaj   +1 more source

ILRI research brief template [PDF]

open access: yes, 2013
You can see examples of products using this template by searching CGSpace for "ILRI research brief" (with the quotation Marks)
International Livestock Research Institute
core  

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

ILRI project brochure template [PDF]

open access: yes, 2012
You can see examples of products using this template by searching CGSpace for "ILRI project brochure" (with the quotation ...
International Livestock Research Institute
core  

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