Results 141 to 150 of about 3,079,577 (277)

mGluR5 in ECCCK to BLA Circuit Modulates Depressive‐Like Phenotypes through CCK Signaling

open access: yesAdvanced Science, EarlyView.
Dysregulation of mGluR5 and CCK signaling contributes to major depressive disorder, yet circuit‐level mechanisms remain unclear. Here, the ECCCK→BLA pathway is identified as a critical regulator of affective behavior. mGluR5 modulates synaptic function and CCK signaling within this circuit, controlling stress susceptibility and depressive‐like states ...
Muhammad Asim   +4 more
wiley   +1 more source

Mechanisms of Hydroxyl Radical Chemistry in Aqueous Solution Triggered by Photoexcitation and Probed by Soft X-rays. [PDF]

open access: yesJ Am Chem Soc
Cordsmeier L   +6 more
europepmc   +1 more source

Tempo do sujeito, tempo do mundo, tempo da clínica

open access: yesRevista Subjetividades, 2004
Ao comparar as concepções do tempo clássico da física e do tempo da subjetividade, o texto coloca em questão, na dimensão do “tempo vivido”, a tese da primazia do futuro, e na dimensão do “tempo do mundo”, a tese da primazia do presente. Algumas considerações complementares dizem respeito ao sentido do tempo na psicanálise, em especial no trauma e no ...
openaire   +2 more sources

Tuned Oxidation Potential of Continuous Defective Photocatalyst for Selective Biomass Conversion

open access: yesAdvanced Science, EarlyView.
This work develops a wavelength‐controlled photocatalytic strategy that utilizes defect‐state excitation to modulate oxidative capability for biomass selective conversion. By tuning the photooxidation potential to match substrate reactivity, the system suppresses overoxidation and enables the selective formation of value‐added products, providing a ...
Longfei Hong   +7 more
wiley   +1 more source

A Metal‐Free Molecular Ferroelectric With Large Piezoelectricity and Its Porous Composite for Superior Output Power Density

open access: yesAdvanced Science, EarlyView.
Metal‐free molecular crystal [(CH3C6H10NH3)(18‐crown‐6)][ClO4] functions as a high‐performance molecular ferroelectric. Through strategic methylation of the cyclohexylamine unit, the compound achieves large spontaneous polarization and outstanding piezoelectric coefficients.
Nan Chen   +4 more
wiley   +1 more source

Crystal Facet‐Polysaccharide Matching in CFS‐P Nanocrystals Drives Fungal Uptake, Vacuole Destruction, and Selective Antifungal Activity

open access: yesAdvanced Science, EarlyView.
Facet‐engineered PVP‐capped CuFeSe2 nanocrystals exhibit potent, selective antifungal activity by strongly binding cell‐wall mannan, enabling vacuolar entry and organelle disruption. High‐index facets show superior mannan affinity, validated by theoretical calculations and experiments. CFS‐P induces vacuolar cavitation, mitochondrial abnormalities, and
Zhaohui Wang   +10 more
wiley   +1 more source

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