Results 21 to 30 of about 3,035,993 (275)

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Microscopic entropy of the three-dimensional rotating black hole of BHT massive gravity

, 2009
Asymptotically AdS rotating black holes for the Bergshoeff-Hohm-Townsend (BHT) massive gravity theory in three dimensions are considered. In the special case when the theory admits a unique maximally symmetric solution, apart from the mass and the ...
Giribet, Gaston, Oliva, Julio, Tempo, David, Troncoso, Ricardo   +3 more
core   +1 more source

Accelerated Progression of Gait Impairment in Parkinson's Disease and REM Sleep Without Atonia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective People with Parkinson's disease (PD) and rapid eye movement (REM) sleep without atonia (RSWA) often have more severe gait disturbances compared to PD without RSWA. The association between the presence and expression of RSWA and the rate of progression of gait impairment in PD is unknown.
Sommer L. Amundsen‐Huffmaster, Jae Woo Chung, Maria E. Linn‐Evans, Matthew N. Petrucci, Chiahao Lu, Destiny J. Weaver, Joshua De Kam, Scott E. Cooper, Paul J. Tuite, Aleksandar Videnovic, Michael J. Howell, Colum D. MacKinnon   +11 more
wiley   +1 more source

Integrable systems with BMS$_{3}$ Poisson structure and the dynamics of locally flat spacetimes [PDF]

, 2017
We construct a hierarchy of integrable systems whose Poisson structure corresponds to the BMS$_{3}$ algebra, and then discuss its description in terms of the Riemannian geometry of locally flat spacetimes in three dimensions. The analysis is performed in
Fuentealba, Oscar, Matulich, Javier, Pino, Miguel, Pérez, Alfredo, Rodríguez, Pablo, Tempo, David, Troncoso, Ricardo   +6 more
core   +2 more sources

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source

Ergodic Randomized Algorithms and Dynamics over Networks [PDF]

, 2013
Algorithms and dynamics over networks often involve randomization, and randomization may result in oscillating dynamics which fail to converge in a deterministic sense.
Frasca, Paolo, Ishii, Hideaki, Ravazzi, Chiara, Tempo, Roberto   +3 more
core  

Life‐Threatening Bradycardia in Anti‐NMDA‐Receptor Encephalitis and a Novel Use for Permanent Pacing

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Pediatric anti‐NMDA receptor encephalitis (pNMDARE) is an autoantibody‐mediated disorder that can cause severe autonomic dysfunction, including symptomatic bradycardia and asystole. Dysautonomia can last for years, making it very challenging to manage.
Sarah Tucker, Abhijit Das, Andres Jimenez, Areeba Basit, Yike Jiang, Emily A. Smitherman, Heather Van Mater, Taylor Howard, Alexander J. Sandweiss, Kristen S. Fisher   +9 more
wiley   +1 more source

Reactivity of TEMPO anion as a nucleophile and its applications for selective transformations of haloalkanes or acyl halides to aldehydes [PDF]

, 2004
Sodium 2,2,6,6-tetramethylpiperidine-N-oxide (TEMPO−Na+), generated by reduction of TEMPO· with sodium naphthalenide in THF, reacted with alkyl halides or acyl halides to produce O-alkylated or acylated TEMPOs, which were in turn oxidized with ...
Allen, Anderson, Boger, Braslau, Braslau, Gilbert, Hawker, Henry-Riyad, Hiroyuki Kawafuchi, Hudlicky, Hunter, Inokuchi, Jahn, Johnstone, Kersey, Kilenyi, Kruse, Matyjaszewski, Nahm, Ollivier, Page, Paquette, Ren, Rossi, Saunders, Schämann, Semmelhack, Sholle, Skene, Studer, Togo, Tsutomu Inokuchi, Uneyama, Wetter, Whitesides, Winterfeldt   +35 more
core   +1 more source

Trends in Dermatopolymyositis Mortality, 1999–2022: A Nationwide Population‐Based Study, United States

Arthritis Care &Research, EarlyView.
We report the national burden of dermatopolymyositis mortality over the past quarter century using the US national vital statistics data. Age‐standardized mortality rates for dermatopolymyositis decreased at an annual rate of 3.8% each year, which was higher than the annual percent decrease for deaths from all other causes.
Elizabeth Matz, Ram R. Singh
wiley   +1 more source

Tempos Líquidos [PDF]

Sociologias, 2010
Esta resenha tem por objetivo fazer emergir as principais ideias de Zygmunt Bauman em Tempos líquidos. Neste sentido, o assunto primordial que permeia a obra é a insegurança. Um fenômeno resultante da "vontade de liberdade", uma marca, segundo o autor, da pós-modernidade, princípio que se opõe diretamente à projeção em torno de uma vida social estável,
openaire   +5 more sources