Results 31 to 40 of about 488,892 (246)

Spatial and temporal dynamics of malaria transmission in rural western Kenya [PDF]

open access: yes, 2012
: BACKGROUND: Understanding the impact of reducing Plasmodium falciparum malaria transmission requires estimates of the relationship between health outcomes and exposure to infectious mosquitoes. However, measures of exposure such as mosquito density and
Amek, N.   +19 more
core   +1 more source

Temporal and spatial distribution characteristics of water resources in Guangdong Province based on a cloud model

open access: yesWater Science and Engineering, 2015
With a focus on the difficulty of quantitatively describing the degree of nonuniformity of temporal and spatial distributions of water resources, quantitative research was carried out on the temporal and spatial distribution characteristics of water ...
Qi Zhou   +4 more
doaj   +2 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

A short geostatistical study of the three-dimensional spatial structure of fumonisins in stored maize [PDF]

open access: yes, 2010
The heterogeneous three-dimensional spatial distribution of mycotoxins has proven to be one of the main limitations for the design of effective sampling protocols.
N. Magan   +12 more
core   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Temporal and spatial distortions in adult amblyopia [PDF]

open access: yes, 2007
Amblyopia is a developmental disorder of the visual system that leads to reduced vision in one or both eyes. People suffering from amblyopia show different perceptual deficits like reduced contrast sensitivity, reduced or no stereopsis, spatial ...
Bäumer, Claudia
core  

Modelling a two-dimensional spatial distribution of mycotoxin concentration in bulk commodities to design effective and efficient sample selection strategies [PDF]

open access: yes, 2009
Mycotoxins in agricultural commodities are a hazard to human and animal health. Their heterogeneous spatial distribution in bulk storage or transport makes it particularly difficult to design effective and efficient sampling plans.
Origgi, Simona   +6 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Research on Spatial-Temporal Variations of Cultivated Land in China Based on GlobeLand30

open access: yesFrontiers in Environmental Science, 2022
The period from 2010 to 2020 is a period of rapid economic development in China, with the increasing population and the urbanization level reaching 63.89%. Cultivated land plays an extremely important role in China’s food security.
Hui Cheng, Xiaowei Wang, Danling Chen
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

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