Results 51 to 60 of about 16,427 (224)

Endothelin-1 promotes vascular smooth muscle cell migration across the artery wall: a mechanism contributing to vascular remodelling and intimal hyperplasia in giant-cell arteritis [PDF]

, 2018
Background: Giant-cell arteritis (GCA) is an inflammatory disease of large/medium-sized arteries, frequently involving the temporal arteries (TA). Inflammation-induced vascular remodelling leads to vaso-occlusive events. Circulating endothelin-1 (ET1) is
Alba, Marco A., Cid Xutglà, M. Cinta, Corbera Bellalta, Marc, Espígol Frigolé, Georgina, Hernández Rodríguez, José, Lavilla Grífols, Rodolfo, Lozano Garcia, Ester, Planas Rigol, Ester, Preciado Gallego, Sara, Prieto González, Sergio, Segarra Blasco, Marta, Terrades García, Nekane   +11 more
core   +1 more source

Quantification of Vascular Burden on Cranial Vessel Wall Magnetic Resonance Imaging and Ophthalmic Complications in Giant Cell Arteritis

ACR Open Rheumatology, Volume 8, Issue 5, May 2026.
Objective There is a need for measures of disease severity for giant cell arteritis (GCA), which may enable identification of high‐risk subgroups (eg, ophthalmic complications) and individualized approaches to therapy. We derived a continuous score using data from cranial vessel wall magnetic resonance imaging (VW‐MRI) to quantify vascular burden in ...
David L. Yang, Quy Cao, Fang Liu, Tara McWilliams, Ryan Rebello, Madhura A. Tamhankar, Shubhasree Banerjee, Rui Liang, Robert M. Kurtz, Joshua F. Baker, Naomi Amudala, Zhaoyang Fan, Jae W. Song, Peter A. Merkel, Jeffrey Morris, Rennie L. Rhee   +15 more
wiley   +1 more source

Pulmonary nodules in a patient with Giant Cell Arteritis

Pulmonology, 2019
Giant Cell Arteritis (GCA) is a common systemic vasculitis that involves medium and large arteries, most frequently extracranial branches of the carotid artery.
D. Pinho dos Santos, J.P. Fonseca, V. Romão, J. Capelo, A. Carragoso   +4 more
doaj   +1 more source

Scalp Necrosis Revealing Severe Giant-Cell Arteritis

Case Reports in Medicine, 2020
Giant-cell arteritis (GCA), also referred to as temporal arteritis, is the most common primary vasculitis of the elderly involving the extracranial branches of the carotid arteries, in particular, the temporal artery.
Safa Idoudi, Marouene Ben Kahla, Fares Mselmi, Badreddine Sriha, A. Guiga, Samia Ayachi, Colandane Belajouza, Mohamed Denguezli   +7 more
doaj   +1 more source

Increased expression of interleukin-22 in patients with giant cell arteritis [PDF]

, 2017
GCA is characterized by arterial remodelling driven by inflammation. IL-22 is an attractive cytokine which acts at the crosstalk between immune and stromal cells.
Alessandro, Riccardo, Belloni, Lucia, Boiardi, Luigi, Bonacini, Martina, Cavazza, Alberto, Ciccia, Francesco, Cimino, Luca, Croci, Stefania, Moramarco, Antonio, Muratore, Francesco, Parmeggiani, Maria, Rizzo, Aroldo, Salvarani, Carlo, Zerbini, Alessandro   +13 more
core   +2 more sources

Giant Cell Arteritis With Mesenteric Involvement and Superimposed Functional Gut Syndrome: A Case Report

Clinical Case Reports, Volume 14, Issue 5, May 2026.
FDG PET‐CT images of giant cell arteritis with mesenteric involvement. ABSTRACT Giant cell arteritis‐associated mesenteric vasculitis is a rare manifestation and often carries significant mortality and morbidity. We present a case of GCA with mesenteric involvement that was at first diagnostically challenging, contributed to by a history of functional ...
Benjamin Rao, Ronan O'Connor
wiley   +1 more source

From Nerves to Vessels: Unmasking Churg‐Strauss Behind Polyneuropathy

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Eosinophilic granulomatosis with polyangiitis (EGPA), formerly Churg‐Strauss vasculitis, is a rare systemic autoimmune disease. Neurological involvement is a significant complication. This report details a case of EGPA with severe, progressive polyneuropathy and atypical serological findings, highlighting diagnostic challenges and the ...
Hiba Antar, Sylvana Balhas, Zeinab El Mawla   +2 more
wiley   +1 more source

Neurological Manifestations, Diagnostics, and Treatment of Giant Cell Arteritis: A Literature Review

Neurologijos seminarai
Giant cell (temporal) arteritis is the most common primary systemic vasculitis. The main manifestation of this disease is new onset headache affecting people over 50 years old with an increased erythrocytes sedimentation rate (≥50mm/h).
Ieva Lukauskaitė, Dalius Jatužis, Jurgita Valaikienė   +2 more
doaj   +1 more source

Influence of the IL17A locus in giant cell arteritis susceptibility [PDF]

, 2017
Objective: Different lines of evidence have highlighted the role of IL-17A in the inflammatory process occurring in giant cell arteritis (GCA). The aim of the present study was to assess whether the IL17A locus influences GCA susceptibility and its ...
Beretta, Lorenzo, Blanco, Ricardo, Boiardi, Luigi, Braun, Niko, Caminal Montero, L., Castañeda, Santos, Cid Xutglà, M. Cinta, Fernández-Contreras, M. E., García-Villanueva, María Jesús, González-Gay, Miguel A., Gómez Vaquero, Carmen, Hernández Rodríguez, José, Latus, J., Martín, Javier, Martínez Taboada, Víctor Manuel, Miguel, Eugenio de, Molberg, O., Monfort, Jordi, Moosig, Frank, Morado, Inmaculada C., Márquez, Ana, Narváez García, Francisco Javier, Ortego Centeno, Norberto, Palm, Oyvind, Pazzola, Giulia, Ramentol, Marc, Salvarani, Carlo, Santaniello, Alessandro, Solans, Roser, Sopeña, Bernardo, Spanish GCA Consortium, Witte, Torsten   +31 more
core   +1 more source

Microscopic Polyangiitis After Pulmonary Nontuberculous Mycobacterial Disease: A Case Report and Literature Review

Respirology Case Reports, Volume 14, Issue 5, May 2026.
This case highlights that ANCA‐associated vasculitis can emerge in patients with chronic airway disease and a history of nontuberculous mycobacterial infection, potentially masquerading as infection‐related inflammation. Early recognition based on extrapulmonary clues (urinary abnormalities and neuropathy) enabled prompt diagnosis and treatment with ...
Hidenori Takahashi, Riho Nakagawa, Mio Toyama‐Kousaka, Yugo Satake, Hiroki Nagamatsu, Ryutaro Hirose, Naoya Toba, Shinichiro Ota, Miwa Morikawa, Natsuko Nakano, Kazuyoshi Ishigaki, Masaharu Shinkai   +11 more
wiley   +1 more source