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Giant Cell Arteritis Presenting With Ocular Symptoms: Clinical Characteristics and Multimodal Imaging in a Chinese Case Series

Frontiers in Medicine, 2022
PurposeTo evaluate demographic and clinical characteristics of a Chinese population with giant cell arteritis using multimodal imaging focusing on ophthalmic examinations.DesignRetrospective observational case series.Materials and MethodsIn the neuro ...
Qian Chen +10 more
doaj +1 more source

The challenge to detect heart transplant rejection and transplant vasculopathy non-invasively - a pilot study [PDF]

, 2009
Background Cardiac allograft rejection and vasculopathy are the main factors limiting long-term survival after heart transplantation. In this pilot study we investigated whether non-invasive methods are beneficial to detect cardiac allograft rejection ...
Helber Uwe +6 more
core +1 more source

Higher complement C4 gene copy number constitutes a shared genetic risk factor for giant cell arteritis and IgA vasculitis

Arthritis &Rheumatology, Accepted Article.
Objective Low copy number (CN) of complement C4 isoforms and high CN of retroviral HERV‐K elements are known risk factors for many immune‐mediated inflammatory diseases (IMIDs), often showing sex‐biased effects. Here, we assessed whether CN variation within the C4 gene contributes to giant cell arteritis (GCA) and IgA vasculitis (IgAV), two complex ...
Laura Martínez‐Gutiérrez +296 more
wiley +1 more source

Antineutrophil Cytoplasmic Antibody–Associated Vasculitis Masquerading as Giant Cell Arteritis

Annals of Internal Medicine: Clinical Cases
The triad of temporal artery tenderness, monocular vision loss, and raised inflammatory markers is suggestive of giant cell arteritis (GCA). We encountered a 76-year-old woman who presented with acute right eye vision loss, temporal tenderness, jaw ...
Nicholas Garcia +3 more
doaj +1 more source

The Microbiome of Temporal Arteries

Pathogens and Immunity, 2019
Objective: A role for microorganisms in giant cell arteritis (GCA) has long been suspected. We describe the microbiomes of temporal arteries from patients with GCA and controls.
Gary Stuart Hoffman +12 more
doaj +1 more source

Ectopic expression of CXCL13, BAFF, APRIL and LT-ß is associated with artery tertiary lymphoid organs in giant cell arteritis [PDF]

, 2016
Objectives To investigate whether artery tertiary lymphoid organs (ATLOs) are present in giant cell arteritis (GCA) and that their formation is associated with the ectopic expression of constitutive lymphoid tissue-homing chemokines.
ALESSANDRO, Riccardo +11 more
core +1 more source

Real‐world characteristics and treatment of cardiac transthyretin amyloidosis: A multicentre, observational study

ESC Heart Failure, Volume 12, Issue 2, Page 1203-1216, April 2025.
The 366 patients diagnosed with transthyretin amyloidosis cardiomyopathy (ATTR‐CM) were analyzed regarding their clinical characteristics in the first year after approval of tafamidis 61 mg for ATTR‐CM in Germany. Nearly two‐thirds of the patients were in an advanced disease stage and 64% met the key criteria of the “Transthyretin Amyloidosis ...
Richard J. Nies +23 more
wiley +1 more source

Temporal Arteritis and Vision Loss in Microscopic Polyangiitis: A Case Report and Literature Review

Case Reports in Nephrology, 2020
Microscopic polyangiitis (MPA) is an idiopathic autoimmune disease characterized by systemic vasculitis. While the lungs and kidneys are the major organs affected by MPA, it is known to involve multiple organ systems throughout the body.
Alexander G. Goglia +3 more
doaj +1 more source

Clinic manifestations in granulomatosis with polyangiitis [PDF]

, 2016
Granulomatosis with polyangiitis (GPA), formerly Wegener's granulomatosis (WG), is an uncommon immunologically mediated systemic small-vessel vasculitis that is pathologically characterised by an inflammatory reaction pattern (necrosis, granulomatous ...
De Vincentiis, Marco +7 more
core +1 more source

Neurotrophins are expressed in giant cell arteritis lesions and may contribute to vascular remodeling [PDF]

, 2014
International audienceIntroduction: Giant cell arteritis (GCA) is characterized by intimal hyperplasia leading to ischaemic manifestations that involve large vessels.
Alexis Régent +15 more
core +2 more sources

giant cell arteritis
biopsy
humans

temporal arteries
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3. good health

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