Results 31 to 40 of about 251,618 (233)

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

TIME IN PROFESSORS’ LIVES THROUGH THE EYES OF SOCIOLOGISTS

Высшее образование в России, 2016
The authors analyze the results of a qualitative study of the temporal behaviour strategies of representatives of the research pedagogical and scientific community, investigate the temporal behaviour strategies in the context of cognitive, emotional and ...
Polina A. Ambarova, Garold E. Zborovsky
doaj  

만족도와 재구매 간 관계에 있어서 상황적 영향의 조절효과에 관한 연구

Asia Marketing Journal, 2010
Although there have been many studies regarding the inconsistency between consumers` attitudes and behavior, prior research has almost exclusively focused on the relationship between the attitude before behavior and the initial behavior.
Min Hoon Lee, Young Won Ha
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

TEMPORAL CHARACTERISTICS AND CONTRADICTIONS OF STUDENT YOUTH

Высшее образование в России, 2016
Student youth is considered as a specific age community. Its development has inherent temporal characteristics and complex temporal contradictions.
Polina A. Ambarova, Garold E. Zborovsky
doaj  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

How machine learning informs ride-hailing services: A survey

Communications in Transportation Research, 2022
In recent years, online ride-hailing services have emerged as an important component of urban transportation system, which not only provide significant ease for residents’ travel activities, but also shape new travel behavior and diversify urban mobility
Yang Liu, Ruo Jia, Jieping Ye, Xiaobo Qu
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Modeling and managing behavior change in groups: A Boolean network method [PDF]

advances.in/psychology
Social influence processes can induce desired or undesired behavior change in individual members of a group. Empirical modeling of group processes and the design of network-based interventions meant to promote desired behavior change is somewhat limited ...
Xiao Yang, Réka Albert, Lauren Molloy Elreda, Nilam Ram   +3 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source