Results 91 to 100 of about 425,396 (311)

Geometry‐Guided Osteogenesis in Bone‐on‐a‐Chip Systems Using Triply Periodic Minimal Surface Scaffolds

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents a bone‐on‐a‐chip platform incorporating TPMS scaffolds to study geometry‐dependent osteogenesis under dynamic flow. By tuning pore shape and solidity, it precisely controls mechanical cues, revealing how topological features and shear stress affect osteogenic differentiation and matrix formation.
Donggyu Kim   +5 more
wiley   +1 more source

Body Biofluids for Minimally‐Invasive Diagnostics: Insights, Challenges, Emerging Technologies, and Clinical Potential

open access: yesAdvanced Healthcare Materials, EarlyView.
Recent advances in diagnostics have accelerated the development of miniaturized wearable technologies for the continuous monitoring of diseases. This paradigm is shifting healthcare away from invasive, centralized blood tests toward decentralized monitoring, using alternative body biofluids.
Lanka Tata Rao   +2 more
wiley   +1 more source

Engineering Complexity: Advances in 3D Breast Cancer Models for Precision Oncology

open access: yesAdvanced Healthcare Materials, EarlyView.
In vitro breast cancer models that closely mimic the complex biological and cellular interactions within the tumor microenvironment hold strong promise for enhancing our understanding of tumor progression, immune system behavior, and resistance to therapies, which are essential for developing personalized cancer treatments. Abstract Engineered in vitro
Wonwoo Jeong, Sang Jin Lee
wiley   +1 more source

AI‐Assisted Design and Evaluation of SLM‐Ti64 Implants for Enhanced Bone Regeneration

open access: yesAdvanced Healthcare Materials, EarlyView.
AI‐driven simulations of biological healing, combining biomechanical modeling and machine learning, enable personalized orthopedic treatments. By decoding healing patterns influenced by implants and patient‐specific factors, this approach advances fracture repair understanding, optimizes implant design, and supports precision medicine and sustainable ...
Muhammad Usama Zaheer   +3 more
wiley   +1 more source

Insidious progressive bone destruction in a dog surgically treated for otitis media: follow-up by clinical examination and computed tomography [PDF]

open access: yes, 2014
A 5.5-year-old Beagle was evaluated for abnormal swallowing and a head tilt of a two-weeks duration. Inspection of the throat and external ear canal revealed an intact but abnormally bulging eardrum.
De Rooster, Hilde   +6 more
core   +1 more source

BMP2 commitment to the osteogenic lineage involves activation of Runx2 by DLX3 and a homeodomain transcriptional network

open access: yes, 2006
Several homeodomain (HD) proteins are critical for skeletal patterning and respond directly to BMP2 as an early step in bone formation. RUNX2, the earliest transcription factor proven essential for commitment to osteoblastogenesis, is also expressed in ...
Aberg   +71 more
core   +1 more source

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