Results 181 to 190 of about 369,446 (359)

Selection maintains floral color polymorphism in scarlet paintbrush, Castilleja coccinea, reflecting combined ecological factors

American Journal of Botany, EarlyView.
Abstract Premise Evolutionary theory predicts polymorphism should be rare; however, intraspecific variation in floral color is common and can be attributed to genetic drift, plasticity, or variable selection. Examining floral color polymorphism both within contact zones and across a species' range can reveal the mechanisms maintaining this variation ...
Emma Fetterly, Anna S. Braum, Chloe (Eun Sun) Kim, Katherine E. Wenzell, Mary V. Ashley, Laura Steger, Jeremie B. Fant   +6 more
wiley   +1 more source

Very High‐Frequency Oscillations in Mesial Temporal Lobe Epilepsy: Identifying the Epileptogenic Zone [PDF]

Stéphane Jean, Yihai Dai, Yan Cui, Donghuo Deng, Zhe Qian, Panashe Tevin Tagu, Weitao Chen, Weihong Liu, Xiaoqiang Wei, Xinrong Fang, Shiwei Song   +10 more
openalex   +1 more source

Levetiracetam reduces abnormal network activations in temporal lobe epilepsy [PDF]

, 2014
Britta Wandschneider, Jason Stretton, Meneka K. Sidhu, María Centeno, Lajos R. Kozák, Mark R. Symms, Pamela J. Thompson, John S. Duncan, Matthias J. Koepp   +8 more
openalex   +1 more source

The Head Circumference Height Index (HCH‐I) to Quantify Relative Macrocephaly and Aid Identification of Hypochondroplasia in Children

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Hypochondroplasia (HCH) is a rare skeletal dysplasia caused by pathogenic variants in the FGFR3 gene. We hypothesized that the relative disproportion between head circumference and height in HCH might be diagnostically informative and generated a simple index of head‐stature disproportion to help pediatricians diagnose HCH.
Moira S. Cheung, Ruggero Lanzafame, Karen J. Low, Tim J. Cole   +3 more
wiley   +1 more source

Personalized biomarkers of multiscale functional alterations in temporal lobe epilepsy. [PDF]

Nat Commun
Xie K, Sahlas E, Ngo A, Chen J, Arafat T, Royer J, Zhou Y, Rodríguez-Cruces R, Dascal A, Caldairou B, Fadaie F, Barnett A, Audrain S, Larivière S, Caciagli L, Pana R, Weil AG, Grova C, Frauscher B, Schrader DV, Zhang Z, Concha L, Bernasconi A, Bernasconi N, Bernhardt BC.   +24 more
europepmc   +1 more source

Construction of pathogenic Sec16a mutation mouse model using CRISPR/Cas9

Animal Models and Experimental Medicine, EarlyView.
Yaqiang Hu et al. engineered a pathogenic Sec16a mutant mouse model using CRISPR/Cas9 technology. They observed that the Sec16a mutant mice displayed diminished learning and memory capabilities, along with a limb‐clasping phenotype upon tail suspension.
Yaqiang Hu, Zhiyang Zeng, Xinyu Ming, Shuming Yin, Yuting Guan, Liangcai Gao, Dali Li   +6 more
wiley   +1 more source

Clinical–Radiological Spectrum of Cerebral Amyloid Angiopathy‐Related Inflammation

Annals of Neurology, EarlyView.
Objective To identify clinical and radiological features of cerebral amyloid angiopathy‐related inflammation (CAA‐ri), and compare these features with those of sporadic CAA, to improve the understanding, diagnosis, and clinical care of CAA‐ri. Methods We retrospectively reviewed routine clinical data from 37 patients with CAA‐ri and 158 patients with ...
Larysa Panteleienko, Gargi Banerjee, Dermot Mallon, Kitti Thiankhaw, Rupert Oliver, Victoria Harvey, Gareth Ambler, Michael Zandi, Hans Rolf Jäger, David J. Werring   +9 more
wiley   +1 more source

Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Have Distinct Prediagnostic Blood Biochemical Profiles

Annals of Neurology, EarlyView.
Objective Identifying modifiable factors influencing amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) risk is important for prevention. Blood biomarkers, particularly cholesterol, have been associated with neurodegenerative risk, but findings in ALS are inconsistent, and data on FTD are limited.
Christos V. Chalitsios, Jiali Gao, Carol A.C. Coupland, Julia Hippisley Cox, Martin R. Turner, Alexander G. Thompson   +5 more
wiley   +1 more source

Dynamics and Mechanism of Off‐ to On‐Switching in Dreiklang a Decoupled Reversibly Switchable Fluorescent Protein

Angewandte Chemie, EarlyView.
Dreiklang is a reversibly switchable fluorescent protein with a unique photohydration/dehydration mechanism. Using complementary transient absorption and femtosecond—microsecond transient IR, we follow the off‐to‐on photo‐dehydration. A multistep process is revealed, where a hundreds‐of‐picoseconds photoreaction is followed by microsecond structural ...
Anam Fatima, Yongle He, Danielle Rosenberger, Gregory M. Greetham, Partha Malakar, Andras Lukacs, Peter J. Tonge, Stephen R. Meech   +7 more
wiley   +2 more sources

Medial temporal lobe lesions reduce visual working memory precision. [PDF]

Brain
Choo Y, Thakurdesai SP, Qadri A, Fruchet OE, Jackson SN, Chatterjee R, Inati SK, Zaghloul KA, Xie W.   +8 more
europepmc   +1 more source