Results 1 to 10 of about 128,898 (315)
Surgical Considerations of Intractable Mesial Temporal Lobe Epilepsy
Brain Sciences, 2018 Surgery of temporal lobe epilepsy is the best opportunity for seizure freedom in medically intractable patients. The surgical approach has evolved to recognize the paramount importance of the mesial temporal structures in the majority of patients with ...
Warren W. Boling
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Interictal epileptiform discharges induce hippocampal–cortical coupling in temporal lobe epilepsy
Nature Medicine, 2016 Interactions between the hippocampus and the cortex are critical for memory. Interictal epileptiform discharges (IEDs) identify epileptic brain regions and can impair memory, but the mechanisms by which they interact with physiological patterns of ...
Jennifer N Gelinas +2 more
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Scientific Reports, 2017 There is a need for diagnostic biomarkers of epilepsy and status epilepticus to support clinical examination, electroencephalography and neuroimaging. Extracellular microRNAs may be potentially ideal biomarkers since some are expressed uniquely within ...
Rana Raoof +16 more
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The Kainic Acid Models of Temporal Lobe Epilepsy
eNeuro, 2021 Experimental models of epilepsy are useful to identify potential mechanisms of epileptogenesis, seizure genesis, comorbidities, and treatment efficacy. The kainic acid (KA) model is one of the most commonly used.
E. Rusina, C. Bernard, A. Williamson
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Whole-brain functional correlates of memory formation in mesial temporal lobe epilepsy
NeuroImage: Clinical, 2021 The mesial temporal lobe is a key region for episodic memory. Accordingly, memory impairment is frequent in patients with mesial temporal lobe epilepsy. However, the functional relevance of potentially epilepsy-induced reorganisation for memory formation
Anna Doll +7 more
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Temporal Lobe Epilepsy and Psychiatric Comorbidity
Frontiers in Neurology, 2021 Most focal seizures originate in the temporal lobe and are commonly divided into mesial and lateral temporal epilepsy, depending upon the neuronal circuitry involved.
Valerio Vinti +6 more
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Molecular expression and functional analysis of genes in children with temporal lobe epilepsy [PDF]
Journal of Integrative Neuroscience, 2019 Temporal lobe epilepsy is the most common form of epilepsy. However, for this type of condition, antiseizure medication is not effective for children.
Xiaojuan Wu, Yajie Wang, Zhenrong Sun, Shouchen Ren, Weili Yang, Yaxian Deng, Chaoxia Tian, Yazhen Yu, Baoqin Gao
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Neural Regeneration Research, 2023 Cognitive impairment is the most common complication in patients with temporal lobe epilepsy with hippocampal sclerosis. There is no effective treatment for cognitive impairment.
Junzi Chen +7 more
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The Temporal Lobe as a Symptomatogenic Zone in Medial Parietal Lobe Epilepsy
Frontiers in Neurology, 2022 Some surgical failures after temporal lobe epilepsy surgery may be due to the presence of an extratemporal epileptogenic zone. Of particular interest is the medial parietal lobe due to its robust connectivity with mesial temporal structures.
Nadim Jaafar +3 more
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MicroRNAs as potential biomarkers in temporal lobe epilepsy and mesial temporal lobe epilepsy
Neural Regeneration Research, 2023 Temporal lobe epilepsy is the most common form of focal epilepsy in adults, accounting for one third of all diagnosed epileptic patients, with seizures originating from or involving mesial temporal structures such as the hippocampus, and many of these ...
Bridget Martinez, Philip V Peplow
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