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Surgical Considerations of Intractable Mesial Temporal Lobe Epilepsy

open access: yesBrain Sciences, 2018
Surgery of temporal lobe epilepsy is the best opportunity for seizure freedom in medically intractable patients. The surgical approach has evolved to recognize the paramount importance of the mesial temporal structures in the majority of patients with ...
Warren W. Boling
doaj   +3 more sources

Surgical Management for drug-resistant Epilepsy in Medial Temporal Lobe Lesions (Al-Azhar experience) [PDF]

open access: yesAl-Azhar International Medical Journal, 2022
Background: The most common cause of drug resistant epilepsy is the temporal lobe seizures especially that caused by medial temporal lobe epileptogenic lesions.
alaa ibrahim, mohamed rashad
doaj   +1 more source

Molecular expression and functional analysis of genes in children with temporal lobe epilepsy [PDF]

open access: yesJournal of Integrative Neuroscience, 2019
Temporal lobe epilepsy is the most common form of epilepsy. However, for this type of condition, antiseizure medication is not effective for children.
Xiaojuan Wu, Yajie Wang, Zhenrong Sun, Shouchen Ren, Weili Yang, Yaxian Deng, Chaoxia Tian, Yazhen Yu, Baoqin Gao
doaj   +1 more source

Whole-brain functional correlates of memory formation in mesial temporal lobe epilepsy

open access: yesNeuroImage: Clinical, 2021
The mesial temporal lobe is a key region for episodic memory. Accordingly, memory impairment is frequent in patients with mesial temporal lobe epilepsy. However, the functional relevance of potentially epilepsy-induced reorganisation for memory formation
Anna Doll   +7 more
doaj   +1 more source

Activation of medial septum cholinergic neurons restores cognitive function in temporal lobe epilepsy

open access: yesNeural Regeneration Research, 2023
Cognitive impairment is the most common complication in patients with temporal lobe epilepsy with hippocampal sclerosis. There is no effective treatment for cognitive impairment.
Junzi Chen   +7 more
doaj   +1 more source

The Temporal Lobe as a Symptomatogenic Zone in Medial Parietal Lobe Epilepsy

open access: yesFrontiers in Neurology, 2022
Some surgical failures after temporal lobe epilepsy surgery may be due to the presence of an extratemporal epileptogenic zone. Of particular interest is the medial parietal lobe due to its robust connectivity with mesial temporal structures.
Nadim Jaafar   +3 more
doaj   +1 more source

MicroRNAs as potential biomarkers in temporal lobe epilepsy and mesial temporal lobe epilepsy

open access: yesNeural Regeneration Research, 2023
Temporal lobe epilepsy is the most common form of focal epilepsy in adults, accounting for one third of all diagnosed epileptic patients, with seizures originating from or involving mesial temporal structures such as the hippocampus, and many of these ...
Bridget Martinez, Philip V Peplow
doaj   +1 more source

Characterizing the phenotype of drug-resistant childhood epilepsy associated with leukemia: A case series

open access: yesEpilepsy & Behavior Reports, 2021
Children with leukemia are at risk for epilepsy due to primary disease or neurotoxic therapies. We describe the phenotypes of drug-resistant epilepsy in 10 children with history of leukemia.Of 10 cases, 6 had features of Lennox-Gastaut syndrome, and 4 ...
Elham Abushanab   +2 more
doaj   +1 more source

Temporal plus epilepsy: the conception should be attack great importance and inquiring

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2021
Mesial temporal lobe epilepsy (mTLE) is thought to be a network disease, most of them are medical intractable epilepsy. Surgery has benefit outcome, unfortunately, 20%-30% patients with mTLE who undergo surgery fail to achive seizure freedom.
WANG Wei⁃wei, WU Xun
doaj   +1 more source

Temporal lobe epilepsy in children

open access: yesJournal of Pediatric Neurosciences, 2008
Temporal lobe epilepsy is a fairly homogenous syndrome in adults, with hippocampal sclerosis being the commonest etiology. In children, temporal lobe epilepsy is more commonly due to cortical dysplasia or tumors.
Jayanti Mani
doaj   +1 more source

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