Results 61 to 70 of about 499,238 (345)
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Developmental Anomalies of Temporal Muscle [PDF]
Surgery: Current Research, 2014 The anatomy of the temporal region is complex. Also there is controversy over the structures that make up the region. Thus than classically described anatomical structures as fascias, temporal muscle, frontal nerve, arteries, the superficial temporal muscle is present in a variable number of cases.
openaire +1 more source
Isoperimetric Partitioning: A New Algorithm for Graph Partitioning [PDF]
, 2003 Temporal structure is skilled, fluent action exists at several nested levels. At the largest scale considered here, short sequences of actions that are planned collectively in prefronatal cortex appear to be queued for performance by a cyclic competitive
Grady, Leo, Schwartz, Eric
core +1 more source
Muscle synergies in neuroscience and robotics: from input-space to task-space perspectives [PDF]
, 2013 In this paper we review the works related to muscle synergies that have been carried-out in neuroscience and control engineering. In particular, we refer to the hypothesis that the central nervous system (CNS) generates desired muscle contractions by ...
Bastien eBerret +7 more
core +4 more sources
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Adaptive Neural Models of Queuing and Timing in Fluent Action [PDF]
, 2003 Temporal structure in skilled, fluent action exists at several nested levels. At the largest scale considered here, short sequences of actions that are planned collectively in prefrontal cortex appear to be queued for performance by a cyclic competitive ...
Bullock, Daniel
core +1 more source
Neuromuscular control of aerodynamic forces and moments in the blowfly, Calliphora vicina [PDF]
, 2004 Flies are among the most agile of flying insects, a capacity that ultimately results from their nervous system's control over steering muscles and aerodynamic forces during flight.
Balint, Claire N., Dickinson, Michael H.
core +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Prague Medical Report, 2022 Intervertebral disc degeneration is a pathological condition associated with the intervertebral disc and is related to functional alterations in the human body.
Nicole Barbosa Bettiol +9 more
doaj +1 more source