Results 61 to 70 of about 2,601,034 (284)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Impairment of gradual muscle adjustment during wrist circumduction in Parkinson's disease [PDF]

, 2011
Purposeful movements are attained by gradually adjusted activity of opposite muscles, or synergists. This requires a motor system that adequately modulates initiation and inhibition of movement and selectively activates the appropriate muscles.
van der Hoeven Johannes H., Leenders Klaus L., Valsan, Gopal, de Jong, Bauke M.; id_orcid, Toxopeus Carolien M., Klaus L. Leenders, Carolien M. Toxopeus, Bauke M. de Jong, Natasha M. Maurits, Bernard A. Conway, Leenders, Klaus L., Gopal Valsan, Bernard A Conway, Johannes H van der Hoeven, Klaus L Leenders, Maurits, Natasha M.; id_orcid, de Jong, Bauke M., Conway Bernard A., Johannes H. van der Hoeven, Maurits, Natasha M., Conway, Bernard A., Carolien M Toxopeus, Natasha M Maurits, Maurits Natasha M., Toxopeus, Carolien M., Valsan Gopal, Bauke M de Jong, van der Hoeven, Johannes H., de Jong Bauke M.   +28 more
core   +6 more sources

The Temporalis Muscle Flap for Palate Reconstruction: Case Series and Review of the Literature

International Archives of Otorhinolaryngology, 2017
Introduction The temporalis myofascial (TM) is an important reconstructive flap in palate reconstruction. Past studies have shown the temporalis myofascial flap to be safe as well as effective. Free flap reconstruction of palate defects is also a popular
Tara Brennan, Tristan M. Tham, Peter Costantino   +2 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Advances in the relationship between temporal muscle thickness and prognosis of patients with glioblastoma: a narrative review

Frontiers in Oncology, 2023
The most dangerous variety of glioma, glioblastoma, has a high incidence and fatality rate. The prognosis for patients is still bleak despite numerous improvements in treatment approaches. We urgently need to develop clinical parameters that can evaluate
Jinhai Tang, Zhenghao Dong, Junxiu Sheng, Ping Yang, Wanying Zhao, Juan Xue, Qizheng Li, Li Lv, Xiupeng Lv   +8 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Case Report: Flap Management in Cochlear Implant to Avoid Magnet Retention Difficulties

Clinical Case Reports
Thick skin flaps can hinder magnet retention in cochlear implants. Supra‐temporal‐muscle receiver coil placement offers a conservative surgical alternative that avoids tissue resection.
Martín Della Giovanna, Fabricio Penida
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source