Results 41 to 50 of about 416,545 (216)
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Effects of the Temporal Variability of Storm Surges on Coastal Flooding
Frontiers in Marine Science, 2020 Assessments of flood exposure and risk are usually conducted for individual events with a specific peak water level and hydrograph, without considering variations in the temporal evolution (duration and intensity) of storm surges. Here we investigate the
Jorid Höffken +4 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Remote Sensing, 2015 During the last decade, great progress has been made by the scientific community in generating satellite-derived global surface soil moisture products, as a valuable source of information to be used in a variety of applications, such as hydrology ...
Chiara Pratola +3 more
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Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Remote Sensing, 2018 As the frequency and intensity of climate extremes are likely to be substantially modified in upcoming decades due to climate warming, an evaluation of the response of interannual vegetation variabilities to climate extremes is imperative.
Weizhe Chen +3 more
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Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
علوم آب و خاک, 2022 This study was conducted to investigate the temporal variations of runoff and rill erosion in various soil textures under different slope gradients. So, a laboratory experiment was set up in three soil textures (loam, clay loam, and sandy clay loam) and ...
A.R. Vaezi, E. Mohammadi
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