Results 81 to 90 of about 1,257,382 (329)
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Лëд и снегThe isotopic composition (δ18O values) of snow layers, constructing snow cover to the time of reaching maximum snow water equivalent (SWE), was compared with the isotopic content of snow precipitated over the whole the winter season 2018/19 on the ...
S. A. Sokratov +7 more
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Remote Sensing, 2018 As the frequency and intensity of climate extremes are likely to be substantially modified in upcoming decades due to climate warming, an evaluation of the response of interannual vegetation variabilities to climate extremes is imperative.
Weizhe Chen +3 more
doaj +1 more source
Sex differences in variability across timescales in BALB/c mice. [PDF]
, 2017 BackgroundFemales are markedly underinvestigated in the biological and behavioral sciences due to the presumption that cyclic hormonal changes across the ovulatory cycle introduce excess variability to measures of interest in comparison to males. However,
Grant, Azure D +4 more
core +2 more sources
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Revista Brasileira de Engenharia Agrícola e Ambiental, 2011 Objetivou-se com o presente trabalho investigar a variabilidade temporal do conteúdo superficial da água no solo, através da reflectometria no domínio do tempo (TDR), em consequência das características de precipitação ocorridas no semiárido pernambucano,
Thais E. M. dos Santos +2 more
doaj +1 more source
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Phytoplanktonic temporal variability in a coastal area of northwestern Baja California
Ciencias Marinas, 1993 A phytoplankton study was barried out in Bahía de Todos Santos from March 1986 to March 1987. Samples were taken monthly at three stations and at depths of 1, 10 and 20 m.
E Millán-Núñez, DH Loya-Salinas
doaj +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source