Results 81 to 90 of about 494,000 (315)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Quality Assessment of the CCI ECV Soil Moisture Product Using ENVISAT ASAR Wide Swath Data over Spain, Ireland and Finland

open access: yesRemote Sensing, 2015
During the last decade, great progress has been made by the scientific community in generating satellite-derived global surface soil moisture products, as a valuable source of information to be used in a variety of applications, such as hydrology ...
Chiara Pratola   +3 more
doaj   +1 more source

Field scale temporal and spatial variability of δ13C, δ15N, TC and TN soil properties : Implications for sediment source tracing

open access: yes, 2019
Use of natural tracers (in particular, δ13C and δ15N, total carbon and nitrogen) for discriminating and apportioning soil sources of eroded sediment has increased.
Collins, A. L.   +5 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Climate Extremes and Their Impacts on Interannual Vegetation Variabilities: A Case Study in Hubei Province of Central China

open access: yesRemote Sensing, 2018
As the frequency and intensity of climate extremes are likely to be substantially modified in upcoming decades due to climate warming, an evaluation of the response of interannual vegetation variabilities to climate extremes is imperative.
Weizhe Chen   +3 more
doaj   +1 more source

Temporal Structure in Sensorimotor Variability: A Stable Trait, But What For? [PDF]

open access: yesComputational Brain & Behavior, 2019
Abstract Human performance shows substantial endogenous variability over time, and this variability is a robust marker of individual differences. Of growing interest to psychologists is the realisation that variability is not fully random, but often exhibits temporal dependencies.
Marlou Nadine Perquin   +3 more
openaire   +2 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Temporal Variation Pattern of Runoff Generation and Rill Erosion in Different Soils and Slope Gradients

open access: yesعلوم آب و خاک, 2022
This study was conducted to investigate the temporal variations of runoff and rill erosion in various soil textures under different slope gradients. So, a laboratory experiment was set up in three soil textures (loam, clay loam, and sandy clay loam) and ...
A.R. Vaezi, E. Mohammadi
doaj  

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

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