Results 81 to 90 of about 1,272,560 (299)

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Variabilidad temporal de la abundancia de Coralliophila abbreviata y Coralliophila caribaea (Mollusca, Coralliophilidae) en un arrecife coralino del Parque Nacional Morrocoy, Venezuela

open access: yesRevista de Biología Tropical, 2008
C. abbreviata y C. caribaea son moluscos coralívoros del Mar Caribe. Evaluamos la variabilidad temporal de la abundancia y los cambios en la estructura de talla de C. abbreviata y C. caribaea en Cayo Sombrero, Venezuela (septiembre 2004-agosto 2005).
Carlos del Mónaco   +2 more
doaj  

Radial dependence of line profile variability in seven O9--B0.5 stars

open access: yes, 2014
Massive stars show a variety of spectral variability: presence of discrete absorption components in UV P-Cygni profiles, optical line profile variability, X-ray variability, radial velocity modulations.
Bouret, J. -C.   +4 more
core   +5 more sources

Transcranial direct current stimulation improves the QT variability index and autonomic cardiac control in healthy subjects older than 60 years [PDF]

open access: yes, 2016
Background: Noninvasive brain stimulation technique is an interesting tool to investigate the causal relation between cortical functioning and autonomic nervous system (ANS) responses.
Di Iorio, Claudia   +9 more
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Effects of the Temporal Variability of Storm Surges on Coastal Flooding

open access: yesFrontiers in Marine Science, 2020
Assessments of flood exposure and risk are usually conducted for individual events with a specific peak water level and hydrograph, without considering variations in the temporal evolution (duration and intensity) of storm surges. Here we investigate the
Jorid Höffken   +4 more
doaj   +1 more source

Terrestrial Consequences of Spectral and Temporal Variability in Ionizing Photon Events [PDF]

open access: yes, 2006
Gamma-Ray Bursts (GRBs) directed at Earth from within a few kpc may have damaged the biosphere, primarily though changes in atmospheric chemistry which admit greatly increased Solar UV. However, GRBs are highly variable in spectrum and duration.
Adrian L. Melott   +4 more
core   +2 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Quality Assessment of the CCI ECV Soil Moisture Product Using ENVISAT ASAR Wide Swath Data over Spain, Ireland and Finland

open access: yesRemote Sensing, 2015
During the last decade, great progress has been made by the scientific community in generating satellite-derived global surface soil moisture products, as a valuable source of information to be used in a variety of applications, such as hydrology ...
Chiara Pratola   +3 more
doaj   +1 more source

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