Results 151 to 160 of about 31,355 (258)

Sappanwood extract modulates hepatic structure–function in hepatomegaly and hepcidin related iron regulatory pathways in a phenylhydrazine induced hemolytic anemia rat model relevant to thalassemia

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Phenylhydrazine (PHZ) induces hemolytic anemia characterized by increased erythrocyte destruction and ineffective erythropoiesis, leading to hepcidin suppression through disruption of the BMP/SMAD signaling pathway. Reduced hepcidin levels enhance intestinal iron absorption and hepatic iron accumulation, leading to hepatic iron overload.
Mohammad Indra Pratama   +5 more
wiley   +1 more source

Perivascular Spaces as Determinants of Amyloid, Tau, and Vascular Biomarker Progression

open access: yesAnnals of Neurology, EarlyView.
Objective Magnetic resonance imaging (MRI)‐visible enlarged perivascular spaces (PVS) are markers of cerebral small vessel disease (SVD) and aging, processes implicated in both neurodegenerative and cerebrovascular pathologies. However, longitudinal positron emission tomography (PET) studies examining PVS as a mechanism underlying Alzheimer's disease ...
Audrey Low   +11 more
wiley   +1 more source

Influence Mechanism of Structural Parameters of a Novel Sleeve‐Shaft Counterrotating Hydrodynamic Cavitation Reactor on Cavitation Characteristics and Performance

open access: yesAsia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT This study systematically investigates the cavitation characteristics of a novel sleeve‐shaft counterrotating (SSCR) hydrodynamic cavitation reactor using computational fluid dynamics (CFD). Based on the RANS framework combined with the SST k–ω turbulence model and the Zwart–Gerber–Belamri cavitation model, the temporal–spatial evolution of ...
Sitong Guan   +7 more
wiley   +1 more source

Re‐evaluation of a soft crested Edmontosaurin, with implications for hadrosaurid life appearance and diversity

open access: yesThe Anatomical Record, EarlyView.
Abstract Hadrosaurid dinosaurs are generally regarded as “crested” or “non‐crested” depending on the presence or absence of a bony cranial crest. At least one supposedly “non‐crested” hadrosaur is known to have possessed a soft tissue cranial crest (or comb), based on an exceptionally preserved “mummified” specimen. Here we redescribe this specimen and
Henry S. Sharpe   +4 more
wiley   +1 more source

Gonadal development in scorpion mud‐turtles, Kinosternon scorpioides, in a controlled environment

open access: yesThe Anatomical Record, EarlyView.
Stage 20 was identified as the critical point for gonadal differentiation in Kinosternon scorpioides, providing key insights into sex determination. These findings enhance conservation strategies by supporting reproductive management and population viability in both in situ and ex situ programs. Abstract Research on gonadal development including sexual
Brenda Braga   +4 more
wiley   +1 more source

Integrating whole‐bone and regional analyses to understand human scapular growth

open access: yesThe Anatomical Record, EarlyView.
Abstract This study investigates ontogenetic changes in human scapular morphology using three‐dimensional geometric morphometrics with whole‐bone and region‐specific analyses. The aim is to evaluate whether the scapula follows a regular developmental pattern and whether its functionally distinct components, the scapular spine (SS) and glenoid fossa ...
Azahara Salazar‐Fernández   +3 more
wiley   +1 more source

Widespread distribution of large silesaurids evidenced by a new record from the Middle Triassic of southwest Gondwana

open access: yesThe Anatomical Record, EarlyView.
The largest silesaurid known from South America is described here, demonstrating that silesaurids reached large body sizes in southwestern Gondwana. This discovery further underscores the widespread geographic distribution and temporal persistence of large silesaurids across Pangea, despite faunal turnovers and environmental events such as the Carnian ...
Rodrigo Temp Müller
wiley   +1 more source

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