Results 191 to 200 of about 30,078 (285)

Lifespan‐Extending Endogenous Metabolites

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
Endogenous metabolites act as mediators of longevity by modulating conserved cellular pathways. We summarize mechanistic evidence linking specific metabolites to lifespan and healthspan benefits across model systems, with discussion of clinical evidence, translational opportunities, and remaining knowledge gaps.
Yizhou Jiang, Jing‐Dong J. Han
wiley   +1 more source

Urologic chronic pelvic pain syndrome 3‐year symptom trajectories: the Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Symptom Patterns Study

open access: yesBJU International, Volume 137, Issue 2, Page 312-322, February 2026.
Objectives To characterise 3‐year pelvic pain and urinary symptom trajectories and to identify baseline factors associated with urologic chronic pelvic pain syndrome (UCPPS) improvement. Patients and Methods The Trans‐Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Symptom Patterns Study was a multicentre, prospective cohort study
Catherine S. Bradley   +16 more
wiley   +1 more source

Restoration's Longevity in Endodontically Treated Teeth: A Machine Learning Survival Analysis From Randomised Clinical Trials

open access: yesInternational Endodontic Journal, Volume 59, Issue 2, Page 251-261, February 2026.
ABSTRACT Aim This prognostic study aims to develop a machine learning (ML) survival model for estimating the longevity (success and survival rate) of restorations in endodontically treated teeth (ETT). Methodology Data were consolidated from four controlled clinical trials conducted in the Netherlands and Brazil, involving 424 patients and 618 ...
Luiz Alexandre Chisini   +7 more
wiley   +1 more source

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