Results 51 to 60 of about 1,552,702 (390)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

De l’émigration à l’immigration Une étude des itinéraires migratoires d’immigrés arrivés en France au cours des années 1920 à 1970

open access: yesRevue d'Histoire Méditerranéenne, 2021
Cet article s’intéresse à la migration d’une population originaire du bassin méditerranéen, Maghreb (Algériens, Marocains, Tunisiens), Europe du Sud (Espagnols, Italiens, Portugais) et de Turquie, (Arméniens, Turcs) ayant quitté leur pays d’origine pour ...
RAMDANI Hacina
doaj  

Political caricature from a XXIth iberoamerican century. A cultural history of present time

open access: yesCulture & History Digital Journal, 2016
In an adverse context for freedom of thought in the so called public sphere, and from the perspective of the history of present time, this study explores the sense that is supposed to have in Latin America one of the “recent disasters” as was the attack ...
Frédérique Langue
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

The Role of Identification in the Self-Concept of Special Educational Needs Students in Inclusive Settings

open access: yesSAGE Open
The education of students with special educational needs (SEN) in mainstream settings has developed considerably in most Western countries in recent decades. This trend is regularly reinforced by various laws and circulars.
Marine Delaval   +2 more
doaj   +1 more source

Du temps aux temporalités : pour une conceptualisation multidisciplinaire

open access: yes, 2014
Ce texte, issu d’un expose oral, a pour objectif de faire progresser les reponses a trois questions qui sont au cœur du projet de la revue Temporalites depuis son premier numero.
C. Dubar
semanticscholar   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

open access: yesFEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori   +8 more
wiley   +1 more source

The Contribution of Basic Psychological Need Satisfaction to Psychological Well-Being via Autonomous Motivation Among Older Adults: A Cross-Cultural Study in China and France

open access: yesFrontiers in Psychology, 2021
According to self-determination theory (SDT), the satisfaction of the universal needs for autonomy, competence, and relatedness is important in order to enhance autonomous motivation, which in turn promotes psychological well-being (PWB), regardless of ...
Minmin Tang   +3 more
doaj   +1 more source

Conquering the Virtual Public': Jean-Paul Sartre's La tribune des temps modernes and the Radio in France [PDF]

open access: yes, 2014
On the evening of Monday, 21 October 1947, La Tribune de Paris – a daily radio programme that provided a forum for discussion and analysis of current events – gave over its nightly news review, from 8:30 to 8:50, to ‘Jean-Paul Sartre et ses ...
Moody, A
core   +1 more source

Valoració objectiva de l’activitat física en sessions d’exercici físic d’un programa multidisciplinari per al tractament de l’obesitat infantil [PDF]

open access: yes, 2016
Antecedents. La inclusió d’exercici físic supervisat en les intervencions per al tractament de l’obesitat infantil és un dels factors que pot determinar la seva eficàcia.
Castro Viñuales, Ivan   +3 more
core   +2 more sources

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