Results 111 to 120 of about 98,513 (288)

Testing airplane fabrics [PDF]

open access: yes
The following considerations determine the strength of airplane fabrics: 1. maximum air forces acting on the surfaces (including local stresses); 2. tensions produced in the fabrics, in the directions of both warp and filling; 3.
Proll, A
core   +1 more source

Pathways to Improvement: Using Psychological Strategies to Help College Students Master Developmental Math [PDF]

open access: yes, 2013
Some 60 percent of the nation's 13 million community college students are unprepared for college-level courses and must enroll in at least one developmental course....[and] less than a quarter of students in developmental math courses earn a degree or ...
Elena Silva, Taylor White
core  

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Development and characterization of composites consisting of woven fabrics with integrated prismatic shaped cavities [PDF]

open access: yes, 2016
Composites are extensively used in automotive, construction, airplanes, wind turbines etc. because of their good mechanical properties such as high specific stiffness, high specific strength and resistance against fatigue. The main issues with composites
De Baere, Ives   +4 more
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Epilogue [PDF]

open access: yes, 1977
Factors that may have been decisive in turning Rancho Santa Ana Botanic Garden into a successful establishment of botanical teaching and a garden devoted to the conservation and showcasing of the native California flora are put forward.
Lenz, Lee W
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

A MODEL OF CORRUPTION IN AN INVESTMENT PROJECT [PDF]

open access: yes
The present paper analyzes the phenomenon of corruption in the context of a Public Works Department (PWD) in a developing country city and examines its tenacity in the face of anticorruption measures.
Sarbajit Chaudhuri, Soumyen Sikdar
core  

Home - About - Disclaimer - Privacy