Results 141 to 150 of about 179,535 (304)

Single-shot third-harmonic spectral diagnostics for tender X-ray FEL pulses using a bent-crystal spectrometer. [PDF]

J Synchrotron Radiat
Arrell C, Lemke H, Prat E.
europepmc   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Leaf Age-Dependent Volatile Cues Influence Host Location and Oviposition Preference of <i>Obolodiplosis robiniae</i> on <i>Robinia pseudoacacia</i>. [PDF]

Insects
Xu W, Zhao J, Wang Q, Bao Z, Xu Y, Wu H, Shi J.   +6 more
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Increasing competition in pharmaceutical tenders: Patents, treatment guidelines, and centralised procurement of Hepatitis C drugs in Brazil. [PDF]

Glob Public Health
Mercadante E.
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Embodied pain, authenticity, and ethics in performance: reflections on tender steps [PDF]

In Tender Steps, a dance-for-film exploring baby loss, I examine how lived experience shapes performance and meaning-making. Rooted in my own grief, the piece reflects how embodiment carries emotional and cultural weight.
Marshall, A.
core  

Food Availability and Environmental Factors Are Associated With Seasonal Variation in Diet Composition and Activity Budgets of Stump-Tailed Macaques (Macaca arctoides) in Hollongapar Gibbon Sanctuary, Assam, India. [PDF]

Am J Primatol
Chanda K, Chetia S, Sarma K, Medhi S, Borthakur MK.   +4 more
europepmc   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Obinutuzumab as salvage anti-CD20 therapy in poly-refractory difficult-to-treat seropositive rheumatoid arthritis. [PDF]

Rheumatol Adv Pract
Monjo-Henry I, Novella-Navarro M, Molinari M, Sanz-Jardón M, Bonilla-Hernán MG, González-Fernández MÁ, Mendieta EM, Plasencia-Rodríguez C.   +7 more
europepmc   +1 more source