Results 91 to 100 of about 62,717 (282)

Vote-Trading in International Institutions [PDF]

open access: yes, 2008
There is evidence that countries trade votes among each other in international institutions on a wide range of issues, including the use of force, trade issues and elections of judges. Vote-trading has been criticized as being a form of corruption, undue
Eldar, Ofer
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Tender Lungs [PDF]

open access: yesJournal of the Royal Society of Medicine, 1997
S, Khan, K, Dolan
openaire   +2 more sources

The impact of market and supply configurations on the costs of tendering in the construction industry [PDF]

open access: yes, 2000
The cost of tendering in the construction industry is widely suspected to be excessive, but there is little robust empirical evidence to demonstrate this.
Greenwood, D.G.   +3 more
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

An in-depth analysis of e-procurement use in UK construction organisations [PDF]

open access: yes, 2010
Eadie et al (2007) show that there are many advantages in the adoption of e-procurement within a construction organisation. However, its uptake within the construction industry has been inadequately researched.
Eadie, Robert   +2 more
core  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Tendering Universal Service Obligations in Liberalized Network Industries [PDF]

open access: yes
In the past decades, several countries have introduced reverse auctions for allocating universal service or public mission subsidies in various industries. Examples include urban transport, air transport and telecommunications.
Christian Jaag, Urs Trinkner
core  

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

The governance of Scottish ferry services [PDF]

open access: yes, 2011
In this paper we argue that the present arrangements for review and implementation of Scottish Ferry policy are not competent and that, in particular the role and functions of Transport Scotland should be replaced by an independent regulator supported ...
Kay, Neil
core  

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