Results 101 to 110 of about 62,717 (282)

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

THE INFLUENCE OF THE IMPLEMENTATION OF E-TENDERING ON THE COMPETITIVENESS OF SMALL AND MEDIUM ENTERPRISES IN CONSTRUCTION INDUSTRY

Economics & Education, 2017
The rapid pace of technological progress during the last years has influenced the construction industry greatly. Due to the increasing electronic integration of the construction processes, the participants have no choice but to embrace all the latest ...
Oleksandr Sydorenko
doaj  

“This is the best income of the commune: for God’s sake, let it be maintained!” The tendering systems of the Dogana dei Paschi of Siena in the 14th and 15th centuries: operation, profits and profile of the contractors

Reti Medievali Rivista
The paper examines the different tendering systems developed before and after the establishment of the Dogana dei Paschi of Siena for the management of pasture revenues in Southern Tuscany between the fourteenth and fifteenth centuries.
Davide Cristoferi
doaj   +1 more source

Mapping the e-business profile and trends in cost management in the UK construction industry [PDF]

, 2012
The advancement of e-business applications and IT infrastructure has had massive impact on construction business processes over the last decade. The added effects of globalisation coupled with global economic recession have forced businesses to implement
Park, Rachael, Perera, Srinath, Rodrigo, Anushi, Udeaja, Chika, Zhou, Lei   +4 more
core  

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Economies of scale and scope in local public transportation [PDF]

The purpose of this study is to analyze the cost structure of a sample of Swiss multi-modal urban transport operators in order to assess economies of scale and scope.
Aurelio Fetz, Massimo Filippini, Mehdi Farsi   +2 more
core  

Sustainable bioplastics manufacturing from renewable sources

FEBS Open Bio, EarlyView.
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto, Marika Avitabile, Michela Famiglietti, Talayeh Kordjazi, Marzieh Moosavi‐Nasab, Odile F. Restaino, Loredana Mariniello   +6 more
wiley   +1 more source

Examination of Regional Transit Service Under Contracting: A Case Study in the Greater New Orleans Region, Research Report 10-09 [PDF]

, 2011
Many local governments and transit agencies in the United States face financial difficulties in providing adequate public transit service in individual systems, and in providing sufficient regional coordination to accommodate transit trips involving at ...
Houtman, Rebecca, Iseki, Hiroyuki, Rivasplata, Charles R., Smith, Adam L.   +3 more
core   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source