Results 1 to 10 of about 45,529 (309)

Platelet-rich plasma in the pathologic processes of tendinopathy: a review of basic science studies

Frontiers in Bioengineering and Biotechnology, 2023
Tendinopathy is a medical condition that includes a spectrum of inflammatory and degenerative tendon changes caused by traumatic or overuse injuries.
Jialin Lu, Jialin Lu, Han Li, Ziyu Zhang, Rui Xu, Jincheng Wang, Hui Jin, Hui Jin   +7 more
doaj   +2 more sources

Large animal models for the study of tendinopathy

Frontiers in Cell and Developmental Biology, 2022
Tendinopathy has a high incidence in athletes and the aging population. It can cause pain and movement disorders, and is one of the most difficult problems in orthopedics. Animal models of tendinopathy provide potentially efficient and effective means to
Guorong Zhang, Guorong Zhang, Xuyan Zhou, Shuang Hu, Ye Jin, Zhidong Qiu   +5 more
doaj   +2 more sources

The clinical diagnosis of Achilles tendinopathy: a scoping review [PDF]

PeerJ, 2021
Background Achilles tendinopathy describes the clinical presentation of pain localised to the Achilles tendon and associated loss of function with tendon loading activities.
Wesley Matthews, Richard Ellis, James Furness, Wayne A. Hing   +3 more
doaj   +3 more sources

Notoginsenoside R1 attenuates tendinopathy through inhibiting inflammation and matrix metalloproteinases expression [PDF]

Frontiers in Pharmacology
Research purposeThe purpose of this study is to demonstrate the effectiveness of Notoginsenoside R1 (NGR1) in treating tendinopathy and to reveal its potential mechanisms.Materials and methodsThis study performed a preliminary network-based assessment of
Qingxin Han, Junying Wu, Yan Li, Yi Tong, Xiaohua Liu, Xiaoqing Hu, Lei Zhang   +6 more
doaj   +2 more sources

ICON 2019: International Scientific Tendinopathy Symposium Consensus: Clinical Terminology [PDF]

British Journal of Sports Medicine, 2019
Persistent tendon pain that impairs function has inconsistent medical terms that can influence choice of treatment.1 When a person is told they have tendinopathy by clinician A or tendinitis by clinician B, they might feel confused or be alarmed at ...
A. Scott, Kipling Squier, H. Alfredson, R. Bahr, J. Cook, Brooke K. Coombes, R. de Vos, S. Fu, A. Grimaldi, Jeremy S. Lewis, N. Maffulli, S. Magnusson, P. Malliaras, S. Mc Auliffe, E. Oei, C. Purdam, J. Rees, E. Rio, Karin Gravare Silbernagel, C. Speed, A. Weir, J. Wolf, I. Akker-Scheek, B. Vicenzino, J. Zwerver   +24 more
semanticscholar   +6 more sources

Increased expression of aggrecan and biglycan mRNA in Achilles tendinopathy [PDF]

, 2005
To determine the expression of mRNA encoding the proteoglycans aggrecan, versican, biglycan and decorin in mid-tendon samples of chronic painful Achilles tendinopathy and ruptured Achilles tendons, compared with normal tendons.
Anthony N. Corps, A. H. N. Robinson, Tomas Movin, Matthew L. Costa, B L Hazleman, Graham P. Riley   +5 more
openalex   +2 more sources

Exploring molecular and cellular signaling pathways: Unraveling the pathogenesis of tendinopathy [PDF]

Journal of Orthopaedic Translation
Despite the long healing duration of tendon injuries, the outcomes of repairs are frequently suboptimal, resulting in persistent pain and reduced functionality.
Zihan Xu, Wenjing Hou, Tao Zhang, Rui Chen, Thomas Skutella   +4 more
doaj   +2 more sources

Pristimerin suppresses AIM2 inflammasome by modulating AIM2-PYCARD/ASC stability via selective autophagy to alleviate tendinopathy

Autophagy, 2023
Macroautophagy/autophagy plays an important role in regulating cellular homeostasis and influences the pathogenesis of degenerative diseases. Tendinopathy is characterized by tendon degeneration and inflammation.
Huaji Jiang, Yingchao Xie, Jiansen Lu, Hongyu Li, Ke Zeng, Zhiqiang Hu, Dan Wu, Jianwu Yang, Zhenxia Yao, Huadan Chen, Xiaoqian Gong, Xiao Yu   +11 more
semanticscholar   +1 more source

Achilles Tendinopathy Pathogenesis and Management: A Narrative Review

International Journal of Environmental Research and Public Health, 2023
The Achilles tendon is the thickest and strongest tendon of the human body, and it is frequently injured during sports activity. The incidence of Achilles tendon pathologies has increased over recent decades, especially in the last few years, because of ...
D. Tarantino, Rosita Mottola, Giuseppina Resta, R. Gnasso, Stefano Palermi, B. Corrado, F. Sirico, C. Ruosi, R. Aicale   +8 more
semanticscholar   +1 more source

Single-cell and spatial transcriptomics reveal changes in cell heterogeneity during progression of human tendinopathy

BMC Biology, 2023
Background Musculoskeletal tissue degeneration impairs the life quality and motor function of many people, especially seniors and athletes. Tendinopathy is one of the most common diseases associated with musculoskeletal tissue degeneration, representing ...
W. Fu, Runze Yang, Jian Li
semanticscholar   +1 more source