Results 91 to 100 of about 34,054 (265)

Computed microtomographic imaging of revascularization during healing of Achilles tendon injury

open access: yesJournal of Anatomy, EarlyView.
This study explores the role of vascularization in tendon healing by comparing physiological and pathological angiogenesis. Using micro‐CT imaging, we identified distinct changes in vascular organization following injury, highlighting the dynamic interplay between angiogenesis and tendon pathology.
Mert Ocak   +6 more
wiley   +1 more source

Expression profiling of metalloproteinases and tissue inhibitors of metalloproteinases in normal and degenerate human achilles tendon [PDF]

open access: yes, 2006
To profile the messenger RNA (mRNA) expression for the 23 known genes of matrix metalloproteinases (MMPs), 19 genes of ADAMTS, 4 genes of tissue inhibitors of metalloproteinases (TIMPs), and ADAM genes 8, 10, 12, and 17 in normal, painful, and ruptured ...
Alfredson   +73 more
core   +1 more source

Prevalence and incidence rate of lower-extremity tendinopathies in a Danish general practice: a registry-based study

open access: yesBMC Musculoskeletal Disorders, 2019
Background Tendinopathies of the lower extremity (e.g. Achilles, patellar, and plantar heel pain) are common in both general and sporting populations. However, the prevalence and incidence in Danish general practice is unknown.
Henrik Riel   +4 more
doaj   +1 more source

Effectiveness of Resistance Training of Masticatory Muscles for Patients With Temporomandibular Disorders: A Systematic Review

open access: yesJournal of Oral Rehabilitation, EarlyView.
ABSTRACT Background Evidence supports the use of exercise for patients with temporomandibular disorders (TMDs). However, previous studies have mainly focused on combined treatment strategies or undefined exercise modalities. Objective This systematic review aims to evaluate the effectiveness of Resistance Training (RT) as a standalone treatment for ...
Giacomo Asquini   +10 more
wiley   +1 more source

Versican splice variant messenger RNA expression in normal human Achilles tendon and tendinopathies [PDF]

open access: yes, 2004
Versican is the principal large proteoglycan expressed in mid-tendon, but its role in tendon pathology is unknown. Our objective was to define the expression of versican isoform splice variant messenger ribonucleic acid (mRNA) in normal Achilles tendons,
Corps, AN   +6 more
core   +2 more sources

Large extracellular vesicles secreted by human iPSC-derived MSCs ameliorate tendinopathy via regulating macrophage heterogeneity

open access: yesBioactive Materials, 2023
Tendinopathy is a common musculoskeletal disorder which results in chronic pain and reduced performance. The therapeutic effect of stem cell derived-small extracellular vesicles (sEVs) for tendinopathy has been validated in recent years. However, whether
Teng Ye   +10 more
doaj  

Acute Lateral Ankle Sprain Impairs Function and Strength Without Altering Muscle or Tendon Stiffness: A Controlled Observational Study

open access: yesOrthopaedic Surgery, EarlyView.
This study used shear‐wave elastography to assess Achilles tendon and calf muscle stiffness following acute lateral ankle sprain (LAS). Despite the expected alterations due to injury and unloading, no significant stiffness changes were observed over 6 weeks. Findings suggest potential compensatory mechanisms preserving tissue mechanical properties post‐
Pedro Bainy Franz   +8 more
wiley   +1 more source

Classification of distinct tendinopathy subtypes for precision therapeutics

open access: yesNature Communications
Rotator cuff tendinopathy is the most common tendinopathy type with the worst prognosis. Conventional treatments often elicit heterogeneous drug responses due to the diversity of tendinopathy.
Chenqi Tang   +21 more
doaj   +1 more source

Nesfatin-1 Promotes the Osteogenic Differentiation of Tendon-Derived Stem Cells and the Pathogenesis of Heterotopic Ossification in Rat Tendons via the mTOR Pathway

open access: yesFrontiers in Cell and Developmental Biology, 2020
Heterotopic ossification (HO) is a pathological condition involved in tendinopathy. Adipokines are known to play a key role in HO of tendinopathy. Nesfatin-1, an 82-amino acid adipokine is closely reportedly associated with diabetes mellitus (DM), which,
Kai Xu   +9 more
doaj   +1 more source

Load and muscle‐dependent changes in triceps surae motor unit firing properties in individuals with non‐insertional Achilles tendinopathy

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Motor unit firing properties of the medial gastrocnemius (MG), lateral gastrocnemius (LG), and soleus (SO) muscles were assessed using high‐density surface electromyography (HD‐sEMG) during isometric plantarflexion contractions at 10%, 40%, and 70% maximal voluntary contraction (MVC) in individuals with non‐insertional Achilles ...
Ignacio Contreras‐Hernandez   +5 more
wiley   +1 more source

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