Results 41 to 50 of about 359,538 (293)

Gene expression and matrix turnover in overused and damaged tendons [PDF]

, 2005
Chronic, painful conditions affecting tendons, frequently known as tendinopathy, are very common types of sporting injury. The tendon extracellular matrix is substantially altered in tendinopathy, and these changes are thought to precede and underlie the
Abbaszade I, Akeson WH, Alfredson H, Amiel D, Archambault J, Astrom M, Bank RA, Banyard J, Benjamin M., Berenson MC, Boot-Handford RP, Brown PD., Cal S, Caterson B, Cawston TE, Cawston TE., Clark IM, Colige A, Colige A, Collins-Racie LA, Corps AN, Corps AN, Curwin SL, Dalton S, Dickinson SC, Eriksen HA, Everts V, Fernandes RJ, Fitzgerald J, Flannery CR, G. P. Riley, Gao G, Gelberman RH, Gillard GC, Gotoh M, Hannafin JA., Hardingham TE, Hashimoto T, Heinemeier K, Ireland D, Jarvinen M, Jozsa L, Jozsa L, Kannus P, Kannus P., Kannus P., Kashiwagi M, Kashiwagi M, Kaushal GP, Kjaer M, Koch M, Koch M, Koshy PJ, Koskinen SO, Kuno K, Langberg H, Langberg H, Langberg H, Leadbetter WB., Lehto M, McCawley LJ, McNeilly CM, Murphy G, Myllyharju J, Nagase H., Pace JM, Patterson-Kane JC, Pierfitte C, Rees SG, Riley G., Riley GP, Riley GP, Riley GP, Riley GP, Riley GP, Riley GP., Samiric T, Samiric T, Sandy JD, Sandy JD, Sandy JD, Sato K, Smith RK, Smith RK, Somerville RP, Tipton CM, Tortorella MD, Tortorella MD, Tsuzaki M, Vankemmelbeke MN, Vogel KG, Waggett AD, Wang P, Woo SLY, Woo SLY, Woo SLY, Yasuda K, Yoshihara Y   +97 more
core   +1 more source

The Lack of a Representative Tendinopathy Model Hampers Fundamental Mesenchymal Stem Cell Research

Frontiers in Cell and Developmental Biology, 2021
Overuse tendon injuries are a major cause of musculoskeletal morbidity in both human and equine athletes, due to the cumulative degenerative damage. These injuries present significant challenges as the healing process often results in the formation of ...
Marguerite Meeremans, Gerlinde R. Van de Walle, Sandra Van Vlierberghe, Catharina De Schauwer   +3 more
doaj   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Using Platelet-Rich Plasma to Reverse the Effects of Tendinopathy and Prevent Tendon Re-rupture after Surgery in Athletes: The Search for a Standardized Protocol [PDF]

, 2016
30-50% of all lesions amateur and professional sports players will experience during activity are related to the tendon. Moreover, the incidence of tendinopathy, a precursor to tendon rupture, is much higher in both of these groups due to excessive ...
Patel, Shiv
core   +1 more source

Contrasting effects of fluoroquinolone antibiotics on the expression of the collagenases, matrix metalloproteinases (MMP)-1 and -13, in human tendon-derived cells [PDF]

, 2005
Fluoroquinolone antibiotics may cause tendon pain and rupture. We reported previously that the fluoroquinolone ciprofloxacin potentiated interleukin (IL)-1ß-stimulated expression of matrix metalloproteinases (MMP)-3 and MMP-1 in human tendon-derived ...
Corps, A.N, Curry, V.A, Harrall, R.L, Hazleman, B.L, Riley, Graham   +4 more
core   +1 more source

Synergistic effect of umbilical cord extracellular vesicles and rhBMP-2 to enhance the regeneration of a metaphyseal femoral defect in osteoporotic rats

Stem Cell Research & Therapy
Background The aim of this study was to evaluate potential synergistic effects of a single, local application of human umbilical cord MSC-derived sEVs in combination with a low dose of recombinant human rhBMP-2 to promote the regeneration of a ...
Amelie Deluca, Andrea Wagner, Patrick Heimel, Christian Deininger, Florian Wichlas, Heinz Redl, Eva Rohde, Herbert Tempfer, Mario Gimona, Andreas Traweger   +9 more
doaj   +1 more source

Closed rupture of the flexor digitorum profundus tendon of little finger: A case report

Indian Journal of Plastic Surgery, 2004
Closed rupture of the FDP tendon is rare. However, whenever they occur the most common site of rupture is the tendon-bone insertion, less frequent site is at the musculo-tendinous junction.
Pawan Agarwal
doaj   +1 more source

Effect of Foot Orthoses on Midfoot Pain and the Volume of Bone Marrow Lesions in the Midfoot: A Randomized Mechanism of Action Study

Arthritis Care &Research, EarlyView.
Objective Foot orthoses are thought to improve pain by potentially modifying internal mechanical forces. To test this, we explored whether foot orthoses can modify patterns of bone marrow lesions (BMLs) in people with midfoot pain. Methods Forty‐two people were recruited with midfoot pain, and magnetic resonance imaging–confirmed midfoot BMLs ...
Jill Halstead, Anne‐Maree Keenan, Philip G. Conaghan, Dennis McGonagle, Anthony C. Redmond   +4 more
wiley   +1 more source

The role of detraining in tendon mechanobiology [PDF]

, 2016
INTRODUCTION: Several conditions such as training, aging, estrogen deficiency and drugs could affect the biological and anatomo-physiological characteristics of the tendon.
Aldini, Nicol\uf2 Nicoli, Della Bella, Elena, Fini, Milena, Frizziero, Antonio, Gasparre, Giuseppe, Masiero, Stefano, Salamanna, Francesca, Vittadini, Filippo   +7 more
core   +4 more sources

Assessment of Skin in Patients With Systemic Sclerosis Using High‐Frequency Ultrasound and Shear Wave Elastography: A Comparative Study With Histology, Molecular, and Clinical Parameters

Arthritis Care &Research, EarlyView.
Objective Ultrasound (US) has been proposed as a potential tool for assessing skin fibrosis in systemic sclerosis (SSc). However, a large‐scale comparison of US‐based assessment with histologic markers of skin fibrosis has not been reported. We evaluated US‐based skin assessments for their face validity (differentiation between involved SSc and healthy
Ruhani Desai, Filemon Tan, Minghua Wu, Jeffery L. Browning, Samuel Theodore, Meng Zhang, Brian Skaug, Harshdeep Singh Chawla, Manmohan Singh, Salavat Aglyamov, Kirill V. Larin, Maureen Mayes, Shervin Assassi   +12 more
wiley   +1 more source