Results 41 to 50 of about 416,394 (364)

Staging achilles tendinopathy using ultrasound imaging: The development and investigation of a new ultrasound imaging criteria based on the continuum model of tendon pathology [PDF]

, 2020
AimTo develop a standardised ultrasound imaging (USI)-based criteria for the diagnosis of tendinopathy that aligns with the continuum model of tendon pathology.
Ellis, Richard, Furness, James W., Hing, Wayne, Matthews, Wesley, Rathbone, Evelyne   +4 more
core   +1 more source

Engineering Cell–ECM–Material Interactions for Musculoskeletal Regeneration

Bioengineering, 2023
The extracellular microenvironment regulates many of the mechanical and biochemical cues that direct musculoskeletal development and are involved in musculoskeletal disease.
Calvin L. Jones, Brian T. Penney, Sophia K. Theodossiou   +2 more
doaj   +1 more source

Inhibition of Tendon Cell Proliferation and Matrix Glycosaminoglycan Synthesis by Non-Steroidal Anti-Inflammatory Drugs in vitro [PDF]

, 2002
The purpose of this study was to investigate the effects of some commonly used non-steroidal anti-inflammatory drugs (NSAIDs) on human tendon. Explants of human digital flexor and patella tendons were cultured in medium containing pharmacological ...
B. L HAZLEMAN, Brandt KD, Day RO, Dingle JT, Dingle JT, Flint M, G. P. RILEY, Gelberman RH, Hugenberg ST, M. COX, Martel-Pelletier J, Pelletier J-P, R. L. HARRALL, Rolf C, S. CLEMENTS, Scott JE, Thomas J   +16 more
core   +1 more source

I.S.Mu.L.T. Achilles Tendon Ruptures Guidelines [PDF]

, 2018
This work provides easily accessible guidelines for the diagnosis, treatment and rehabilitation of Achilles tendon ruptures. These guidelines could be considered as recommendations for good clinical practice developed through a process of systematic ...
Alessio Giai Via,, Alfonso Maria Forte,, Angelo De Carli,, Anna, Collina, Antonio, Vadal\ue0, Asmaa, Mahmoud, Bernardi, Gabriele, Bernardo, Innocenti, Biagio, Moretti, Biz, Carlo, Calogero, Foti, Carlotta, Galeone, Clelia, Rugiero, Daniela, Buonocore, Domenico, Lupariello, Edoardo, Gaj, Eleonora, Piccirilli, Emanuela, Marsilio, Fantoni, Ilaria, Finotti, Paolo, Francesca, Veronesi, Francesco Di Pietto,, Frizziero, Antonio, Gamberini, Jacopo, Gasparini, Monica, Imma Di Lanno,, Johnny, Padulo, Leonardo, Pellicciari, Luca, Perazzo, Luigi Di Lorenzo,, Manuela, Verri, Marcello, Zappia, Maria Chiara Vulpiani,, Mario, Vetrano, Matteo, Baldassarri, Maurizia, Dossena, Michela, Bossa, Milena, Fini, Nicola, Maffulli, Oliva, Francesco, Pasquale, Farsetti, Pietro, Picerno, Roberto, Buda, Ruggieri, Pietro, Simone, Natali, Umberto, Tarantino, Vincenzo De Luna,, Vito, Chianca   +47 more
core   +1 more source

Do Outcomes of Arthroscopic Subscapularis Tendon Repairs Depend on Rotator Cuff Fatty Infiltration? [PDF]

, 2020
Background:Rotator cuff fatty infiltration has been correlated with poorer radiographic and clinical outcomes in supraspinatus and infraspinatus tendon repairs, but this has not been well-studied in subscapularis tendon repairs.
Feeley, Brian T, Flores, Sergio E, Lansdown, Drew A, Ma, C Benjamin, Monroe, Emily J, Zhang, Alan L   +5 more
core   +1 more source

Tendon proper- and peritenon-derived progenitor cells have unique tenogenic properties. [PDF]

, 2014
IntroductionMultipotent progenitor populations exist within the tendon proper and peritenon of the Achilles tendon. Progenitor populations derived from the tendon proper and peritenon are enriched with distinct cell types that are distinguished by ...
Adams, Sheila M, Birk, David E, Mienaltowski, Michael J   +2 more
core   +1 more source

Electrospun Scaffold Micro-Architecture Induces an Activated Transcriptional Phenotype within Tendon Fibroblasts

Frontiers in Bioengineering and Biotechnology, 2022
Biomaterial augmentation of surgically repaired rotator cuff tendon tears aims to improve the high failure rates (∼40%) of traditional repairs. Biomaterials that can alter cellular phenotypes through the provision of microscale topographical cues are now
Mathew J. Baldwin, Jolet Y. Mimpen, Adam P. Cribbs, Edward Stace, Martin Philpott, Stephanie G. Dakin, Andrew J. Carr, Sarah JB. Snelling   +7 more
doaj   +1 more source

MicroRNA29a regulates IL-33-mediated tissue remodelling in tendon disease [PDF]

, 2015
MicroRNA (miRNA) has the potential for cross-regulation and functional integration of discrete biological processes during complex physiological events.
Akbar, Moeed, Campbell, Abigail L., Gilchrist, Derek, Kerr, Shauna C., Kurowska-Stolarska, Mariola, Liew, Foo Y., McInnes, Iain B., Millar, Neal L., Murrell, George A.C., Reilly, James H.   +9 more
core   +1 more source

Long‐Term Evaluation of Givinostat in Duchenne Muscular Dystrophy, and Natural History Comparisons

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives This ongoing, open‐label extension study is evaluating the long‐term safety, tolerability, and efficacy of givinostat, a Class I and II histone deacetylase inhibitor, in patients with Duchenne muscular dystrophy (DMD). Methods The recruited patients completed one of two prior clinical studies (one Phase 2 and one Phase 3 [EPIDYS ...
Craig M. McDonald, Michela Guglieri, Dragana Vučinić, Gyula Acsadi, John F. Brandsema, Claudio Bruno, Erika L. Finanger, Amy Harper, Mercedes Lopez Lobato, Riccardo Masson, Nuria Muelas, Francina Munell, Yoram Nevo, Yann Péréon, Han Phan, Valeria A. Sansone, Mariacristina Scoto, Tracey Willis, Richard S. Finkel, Krista Vandenborne, Sara Cazzaniga, Silvia Montrasio, Federica Alessi, Paolo Bettica, Eugenio Mercuri, for the Givinostat Study 51 Investigators, the Cooperative International Neuromuscular Research Group (CINRG) Duchenne Natural History Study (DNHS) Investigators, the ImagingDMD Investigators, Enrico Bertini, Giacomo Pietro Comi, Eugenio Maria Mercuri, Giuseppe Vita, Sonia Messina, Claudio Bruno, Riccardo Masson, Valeria Sansone, Nathalie Goemans, Liesbeth De Waele, Laurent Servais, Teresa Gidaro, Odile Boespflug‐Tanguy, Yann Péréon, Jessika Johannsen, Astrid Blaschek, Ulrike Schara‐Schmidt, Erik Niks, Imelda de Groot, Saskia Houwen‐van Opstal, Andres Nascimento, Juan Jesus Vilchez, Nuria Muelas, Francina Munell, Marcos Madruga Garrido, Mercedes Lopez Lobato, Michaela Guglieri, Tracey Willis, Stefan Spinty, Daniel Hawcutt, Mariacristina Scoto, Jean K. Mah, Laura McAdam, Kathryn Selby, Katherine Mathews, Craig McDonald, Craig Zaidman, Barry Byrne, John Brandsema, Gyula Acsadi, Chamindra Laverty, Amy Harper, Erika Finanger, Han Phan, Yoram Nevo, Vedrana Milic Rasic, Dragana Vucinic   +74 more
wiley   +1 more source

Tendinopathy: The Interplay between Mechanical Stress, Inflammation, and Vascularity

Advanced Science
Tendinopathy is a long‐lasting, debilitating disease that not only affects patients' individual lives, but also imposes a significant socioeconomic burden.
Renate Gehwolf, Herbert Tempfer, Nevra Pelin Cesur, Andrea Wagner, Andreas Traweger, Christine Lehner   +5 more
doaj   +1 more source