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Tendon Healing: Repair and Regeneration
Annual Review of Biomedical Engineering, 2012Injury and degeneration of tendon, the soft tissue that mechanically links muscle and bone, can cause substantial pain and loss of function. This review discusses the composition and function of healthy tendon and describes the structural, biological, and mechanical changes initiated during the process of tendon healing.
Pramod B Voleti, Mark R Buckley
exaly +3 more sources
Bioengineering & Translational Medicine, 2022
A crucial component of the musculoskeletal system, the tendon is one of the most commonly injured tissues in the body. In severe cases, the ruptured tendon leads to permanent dysfunction.
Xue Xu +12 more
semanticscholar +1 more source
A crucial component of the musculoskeletal system, the tendon is one of the most commonly injured tissues in the body. In severe cases, the ruptured tendon leads to permanent dysfunction.
Xue Xu +12 more
semanticscholar +1 more source
Foot and Ankle Clinics, 2007
An understanding of the processes of tendon healing and tendon-to-bone healing is important for the intraoperative and postoperative management of patients with tendon ruptures or of patients requiring tendon transfers in foot and ankle surgery. Knowledge of the normal process allows clinicians to develop strategies when normal healing fails.
Matthew, Hope, Terry S, Saxby
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An understanding of the processes of tendon healing and tendon-to-bone healing is important for the intraoperative and postoperative management of patients with tendon ruptures or of patients requiring tendon transfers in foot and ankle surgery. Knowledge of the normal process allows clinicians to develop strategies when normal healing fails.
Matthew, Hope, Terry S, Saxby
openaire +2 more sources
Plastic and Reconstructive Surgery, 1993
An experimental model was developed to study the process of fetal tendon healing. The flexor digitorum profundus tendons of the right hindlimb of 14 fetal lambs were partially lacerated at 100 days' gestation (term 145 days) and then studied macroscopically and histologically at several postinjury intervals (2, 4, 7, 14, 28, 42, and 56 days); two lambs
Mohammad M. Al-Qattan +4 more
openaire +3 more sources
An experimental model was developed to study the process of fetal tendon healing. The flexor digitorum profundus tendons of the right hindlimb of 14 fetal lambs were partially lacerated at 100 days' gestation (term 145 days) and then studied macroscopically and histologically at several postinjury intervals (2, 4, 7, 14, 28, 42, and 56 days); two lambs
Mohammad M. Al-Qattan +4 more
openaire +3 more sources
Hand Clinics, 1985
Concepts of flexor tendon healing suggest that repair is accomplished both by extrinsic peripheral fibroblasts and by intrinsic fibroblasts from the tendon itself. Recent studies indicate that although peripheral adhesions are associated with tendon healing, they are not essential to the repair process.
P R, Manske, R H, Gelberman, P A, Lesker
openaire +2 more sources
Concepts of flexor tendon healing suggest that repair is accomplished both by extrinsic peripheral fibroblasts and by intrinsic fibroblasts from the tendon itself. Recent studies indicate that although peripheral adhesions are associated with tendon healing, they are not essential to the repair process.
P R, Manske, R H, Gelberman, P A, Lesker
openaire +2 more sources
Growth factors and tendon healing
Scottish Medical Journal, 2010Recent attention has focused on the biological pathways by which tendons heal leading to the identification of some growth factors (GFs) with involvement in this process. No studies have been published on the time course of the various GFs during tendon healing process in vivo, in humans.
Oliva F +4 more
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Journal of Hand Surgery, 1988
Significant changes in the concepts of tendon physiology and tendon healing have occurred in the last decade. Nevertheless, they reflect questions and controversies which date back many hundreds of years. Investigators and clinicians of today must recognise that, like their predecessors with an interest in flexor tendon surgery, they will contribute to
openaire +2 more sources
Significant changes in the concepts of tendon physiology and tendon healing have occurred in the last decade. Nevertheless, they reflect questions and controversies which date back many hundreds of years. Investigators and clinicians of today must recognise that, like their predecessors with an interest in flexor tendon surgery, they will contribute to
openaire +2 more sources
Biomechanics of tendon healing
Journal of Biomechanics, 1982The biomechanics of tendon healing was investigated with unsutured rat achilles tendons. After two, three, and four weeks of healing tensile parameters were assayed with a bone-muscle-tendon-bone preparation elongated to failure at a controlled physiological strain rate.
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Clinics in Podiatric Medicine and Surgery, 2005
Tendon connects muscle to bone and functions to transmit muscular forces across joints to stabilize or move those joints. Tendons in the foot and ankle are subject to enormous loads and consequently make up a substantial portion of the body's tendon injuries. Understanding the mechanisms of these injuries requires an understanding of the relative rates
openaire +2 more sources
Tendon connects muscle to bone and functions to transmit muscular forces across joints to stabilize or move those joints. Tendons in the foot and ankle are subject to enormous loads and consequently make up a substantial portion of the body's tendon injuries. Understanding the mechanisms of these injuries requires an understanding of the relative rates
openaire +2 more sources