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Recent Progress in Flexor Tendon Healing

Journal of Hand Therapy, 2002
Although advances in the treatment of flexor tendon injuries have led to improved clinical outcomes during the past several decades, a subset of patients continue to experience a loss of function. Using a canine model of sharp transection of the flexor digitorum profundus tendon followed by repair and rehabilitation using clinically relevant techniques,
Matthew J, Silva   +2 more
openaire   +2 more sources

Is the Tendon Embryogenesis Process Resurrected during Tendon Healing?

Plastic and Reconstructive Surgery, 2003
The process of embryonic tendon development, including the nature and purpose of collagen fibril segments, is reviewed. It is proposed that tendon fibrillogenesis of repair is related to the fibrillogenesis of tendon embryonic development. The assembly of collagen fibril segment units into longer fibers occurs on the surface of tendon fibroblasts in ...
John M, Ingraham   +2 more
openaire   +2 more sources

Tendon: Principles of Healing and Repair

Seminars in Plastic Surgery, 2021
AbstractTendon stores, releases, and dissipates energy to efficiently transmit contractile forces from muscle to bone. Tendon injury is exceedingly common, with the spectrum ranging from chronic tendinopathy to acute tendon rupture. Tendon generally develops according to three main steps: collagen fibrillogenesis, linear growth, and lateral growth.
Christian, Chartier   +5 more
openaire   +2 more sources

Book-Shaped Acellular Fibrocartilage Scaffold with Cell-loading Capability and Chondrogenic Inducibility for Tissue-Engineered Fibrocartilage and Bone-Tendon Healing.

ACS Applied Materials and Interfaces, 2019
Functional fibrocartilage regeneration is a bottleneck during bone-tendon healing, and the currently available tissue-engineering strategies for fibrocartilage regeneration are insufficient because of a lack of appropriate scaffold that can load large ...
Can Chen   +11 more
semanticscholar   +1 more source

Primary tendon healing: A review

The Journal of Hand Surgery, 1977
Clinical and experimental studies on primary tendon healing are reviewed and correlated. Emphasis is placed on the importance of blending the extratendinous and intratendinous elements of tendon healing to obtain optimal functional results. Studies which demonstrate the ability of tendon cells to metabolize, proliferate, and secrete collagen when ...
openaire   +2 more sources

Tendon healing in presence of chronic low-level inflammation: a systematic review.

British Medical Bulletin, 2019
BACKGROUND Tendinopathy is a common musculoskeletal condition affecting subjects regardless of their activity level. Multiple inflammatory molecules found in ex vivo samples of human tendons are related to the initiation or progression of tendinopathy ...
Emanuele Chisari   +3 more
semanticscholar   +1 more source

Tendon, tendon healing, hyperlipidemia and statins.

Muscles, ligaments and tendons journal, 2013
Both hyperlipidemia and metabolic syndrome have adverse effect on tendon structure. Atorvastatin is most widely used antihyperlipidemic drug. Statins have adverse effects on the tendon. Many studies have analyzed the relationship between atorvastatin and skeletal muscles.
Esenkaya, Irfan, Unay, Koray
openaire   +1 more source

[Current aspects of tendon healing].

Der Orthopade, 2000
This review describes structure, function and healing of tendinous tissue and discusses new biologically based treatment options to modulate tendon healing. The repair process after tendon rupture results in a morphologically different and biomechanically inferior structure compared to a normal tendon. The collagen fibril diameters are decreased months
Mòˆller HD, Evans CH, MAFFULLI, Nicola
openaire   +3 more sources

Augmentation of Tendon-to-Bone Healing

Journal of Bone and Joint Surgery, 2014
Tendon-to-bone healing is vital to the ultimate success of the various surgical procedures performed to repair injured tendons. Achieving tendon-to-bone healing that is functionally and biologically similar to native anatomy can be challenging because of the limited regeneration capacity of the tendon-bone interface.
Kivanc, Atesok   +7 more
openaire   +2 more sources

Early Achilles tendon healing in sheep

Archives of Orthopaedic and Trauma Surgery, 2008
The biomechanics of early tendon healing is important for designing post-injury training, but this has not been described in an animal model, similar to humans in size. We measured elastic and viscoelastic properties of a tendon regenerate in sheep, in a study designed to see the effects of exogenously applying the growth and differentiation factor ...
Olena, Virchenko   +3 more
openaire   +2 more sources

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