Results 31 to 40 of about 862,528 (395)
Basic Research on Tendon Repair: Strategies, Evaluation, and Development
Frontiers in Medicine, 2021 Tendon is a fibro-elastic structure that links muscle and bone. Tendon injury can be divided into two types, chronic and acute. Each type of injury or degeneration can cause substantial pain and the loss of tendon function. The natural healing process of
Zhi Jie Li +5 more
doaj +1 more source
Enhanced tendon healing by a tough hydrogel with an adhesive side and high drug-loading capacity
Nature Biomedical Engineering, 2021 Hydrogels that provide mechanical support and sustainably release therapeutics have been used to treat tendon injuries. However, most hydrogels are insufficiently tough, release drugs in bursts, and require cell infiltration or suturing to integrate with
B. Freedman +16 more
semanticscholar +1 more source
Scleraxis lineage cells contribute to organized bridging tissue during tendon healing and identify a subpopulation of resident tendon cells [PDF]
bioRxiv, 2019 During tendon healing, it is postulated that intrinsic tendon cells drive tissue regeneration while extrinsic cells drive pathological scar formation. Intrinsic tendon cells are frequently described as a homogenous, fibroblast population that is positive
Katherine T. Best, Alayna E. Loiselle
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Bone & Joint Research, 2022 Tendon is a bradytrophic and hypovascular tissue, hence, healing remains a major challenge. The molecular key events involved in successful repair have to be unravelled to develop novel strategies that reduce the risk of unfavourable outcomes such as non-
G. Schulze-Tanzil +4 more
semanticscholar +1 more source
Journal of Nanobiotechnology, 2023 Tendon–bone insertion (TBI) injuries, such as anterior cruciate ligament injury and rotator cuff injury, are the most common soft tissue injuries.
Jiaxuan Zou +10 more
semanticscholar +1 more source
Transforming growth factor-β signalling pathway in tendon healing
Growth Factors, 2022 Transforming growth factor-β(TGF-β) plays an important but diverse role in tendon injuries, such as collagen synthesis, cell proliferation, cell differentiation, and cell adhesion, leading to tendon healing and tendon fibrosis.
Yujie Li +8 more
semanticscholar +1 more source
Innate and adaptive immune system cells implicated in tendon healing and disease.
European Cells & Materials, 2022 Tendons perform a critical function in the musculoskeletal system by integrating muscle with skeleton and enabling force transmission. Damage or degeneration of these tissues lead to impaired structure and function, which often persist despite surgical ...
G. Crosio, A.H. Huang
semanticscholar +1 more source
Stem cell research & therapeutics, 2021 The use of adipose-derived mesenchymal stromal cell-derived exosomes (ADSC-Exos) may become a new therapeutic method in biomedicine owing to their important role in regenerative medicine.
Hengchen Liu +7 more
semanticscholar +1 more source
Biological and Mechanical Factors and Epigenetic Regulation Involved in Tendon Healing
Stem Cells International, 2023 Tendons are an important part of the musculoskeletal system. Connecting muscles to bones, tendons convert force into movement. Tendon injury can be acute or chronic.
Zhi Jie Li +2 more
doaj +1 more source
The Functions and Mechanisms of Basic Fibroblast Growth Factor in Tendon Repair
Frontiers in Physiology, 2022 Tendon injury is a disorder of the musculoskeletal system caused by overuse or trauma, which is characterized by pain and limitations in joint function.
Jingwei Lu +12 more
doaj +1 more source