EGR1 Regulates Transcription Downstream of Mechanical Signals during Tendon Formation and Healing. [PDF]
PLoS ONE, 2016 Tendon is a mechanical tissue that transmits forces generated by muscle to bone in order to allow body motion. The molecular pathways that sense mechanical forces during tendon formation, homeostasis and repair are not known.
Ludovic Gaut +5 more
doaj +1 more source
Di-san junyi daxue xuebao, 2019 Objective To evaluate the effect of mechanical stretching in promoting tendon healing and reducing tendon adhesion during the healing of extensor flexor tendon in rats and its effects on the expression of transforming growth factor-β3 (TGF-β3) and cyclic
LI Shuaifeng +4 more
doaj +1 more source
Establishing in vivo and ex vivo chick embryo models to investigate fetal tendon healing
Scientific Reports, 2023 Injured adult tendons heal fibrotically and possess high re-injury rates, whereas fetal tendons appear to heal scarlessly. However, knowledge of fetal tendon wound healing is limited due in part to the need for an accessible animal model.
Phong K. Nguyen +4 more
doaj +1 more source
Use of Posterior Hamstring Harvest During Anterior Cruciate Ligament Reconstruction in the Pediatric and Adolescent Population. [PDF]
, 2018 Background:Posterior hamstring harvest has been described in the adult population in a limited fashion, but no study is available describing the use of posterior hamstring harvest in an active pediatric and adolescent cohort.
Janghala, Abhinav +2 more
core +2 more sources
Biological fixation in anterior cruciate ligament surgery
Asia-Pacific Journal of Sports Medicine, Arthroscopy, Rehabilitation and Technology, 2014 Successful anterior cruciate ligament (ACL) reconstruction with tendon graft requires extensive tendon-to-bone healing in the bone tunnels and progressive graft ligamentization for biological, structural, and functional recovery of the ACL.
Chih-Hwa Chen, Chian-Her Lee
doaj +1 more source
Effect of tendon hydrogel on healing of tendon injury
Experimental and Therapeutic Medicine, 2017 Hand trauma arising from postoperative acute or chronic tendon injuries leads to delayed union and is one of the greatest challenges in clinical practice. The present study hypothesized that an extracellular matrix hydrogel made from tendons can promote tendon healing and improve tissue regeneration.
Quanrong Zhang +6 more
openaire +3 more sources
Tendon mechanobiology in small-animal experiments during post-transection healing [PDF]
European Cells & Materials, 2021 Ruptures to tendons are common and costly, and no clinical consensus exists on the appropriate treatment and rehabilitation regimen to promote their healing as well as full recovery of functionality.
T Notermans +3 more
doaj +1 more source
Effect of pirfenidone on tendon healing
Turkish Journal of Plastic Surgery, 2023 Background: The most critical issues in tendon healing include tendon adhesions and a loss of tendon strength. Adhesions result from fibrotic tissues developing in both surrounding tissues and tendons. Materials and Methods: Twenty-four rats were divided into two groups.
Aydinli, Yasemin +3 more
openaire +3 more sources
Deletion of EP4 in S100a4-lineage cells reduces scar tissue formation during early but not later stages of tendon healing [PDF]
, 2017 Tendon injuries heal via scar tissue rather than regeneration. This healing response forms adhesions between the flexor tendons in the hand and surrounding tissues, resulting in impaired range of motion and hand function.
Ackerman, Jessica E +3 more
core +2 more sources
The effect of adipose-derived stem cell sheets and CTGF on early flexor tendon healing in a canine model [PDF]
, 2014 Oral History interview of Curt Sawyer.
Shen, Hua +7 more
core +2 more sources