Results 71 to 80 of about 862,528 (395)

A novel engineered purified exosome product patch for tendon healing: An explant in an ex vivo model

Journal of Orthopaedic Research, 2020
Reducing tendon failure after repair remains a challenge due to its poor intrinsic healing ability. The purpose of this study is to investigate the effect of a novel tissue‐engineered purified exosome product (PEP) patch on tendon healing in a canine ex ...
Guidong Shi, Yicun Wang, Zhanwen Wang, A. Thoreson, Daniel S Jacobson, P. Amadio, A. Behfar, S. Moran, Chunfeng Zhao   +8 more
semanticscholar   +1 more source

Daratumumab Treatment for Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP): A Case Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an immune‐mediated neuropathy featuring progressive weakness, sensory deficits, and areflexia. While corticosteroids, intravenous immunoglobulin, and plasmapheresis are effective first‐line immunotherapies, a subset of patients remains treatment‐refractory.
Xueyu Zhang, Jianli Zhao, Xue Zhao, Xiaowei Hu, Zichun Xiao, Jie Wu, Xiaowen Li, Jing Xu, Yu‐Jing Li   +8 more
wiley   +1 more source

Graft healing in anterior cruciate ligament reconstruction

Sports Medicine, Arthroscopy, Rehabilitation, Therapy & Technology, 2009
Successful anterior cruciate ligament reconstruction with a tendon graft necessitates solid healing of the tendon graft in the bone tunnel. Improvement of graft healing to bone is crucial for facilitating an early and aggressive rehabilitation and ...
Chen Chih-Hwa
doaj   +1 more source

Active Auxetic Heel Support for Achilles Tendon Therapy [PDF]

, 2018
The Achilles tendon, which stretches from the calf to the ankle, can be injured due to repeated daily activities or overstretching. In severe cases a tear in the tendon can prevent athletes from performing in games as well as individuals from completing ...
Hinrichs, Anna, Malukhina, Kseniya, Sharma, Ishaan, Vierra, Micaela   +3 more
core   +1 more source

Circadian Rhythm‐Regulated ADSC‐Derived sEVs and a Triphasic Microneedle Delivery System to Enhance Tendon‐to‐Bone Healing

Advances in Materials
Modulating the inflammatory microenvironment to reconstruct the fibrocartilaginous layer while promoting tendon repair is crucial for enhancing tendon‐to‐bone healing in rotator cuff repair (RCR), a persistent challenge in orthopedics.
Wei Song, Ying Guo, Wencai Liu, Yijing Yao, Xuancheng Zhang, Zhuochang Cai, Chenrui Yuan, Xin Wang, Yifei Wang, Xiping Jiang, Haoyuan Wang, Weilin Yu, Haiyan Li, Yanlun Zhu, Lingzhi Kong, Yaohua He   +15 more
semanticscholar   +1 more source

Exosomes from tendon stem cells promote injury tendon healing through balancing synthesis and degradation of the tendon extracellular matrix

Journal of Cellular and Molecular Medicine, 2019
Tendon injuries are common musculoskeletal system disorders in clinical, but the regeneration ability of tendon is limited. Tendon stem cells (TSCs) have shown promising effect on tissue engineering and been used for the treatment of tendon injury ...
Yunjiao Wang, Gang He, Yupeng Guo, Hong Tang, Youxing Shi, Xuting Bian, Min Zhu, Xia Kang, Mei Zhou, Jingtong Lyu, Mingyu Yang, M. Mu, Fan Lai, K. Lu, Wan Chen, Bing-hua Zhou, Jiqiang Zhang, K. Tang   +17 more
semanticscholar   +1 more source

ALS With and Without Upper Motor Neuron Signs: A Comparative Study Supporting the Gold Coast Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The Gold Coast criteria permit diagnosis of amyotrophic lateral sclerosis (ALS) even without upper motor neuron (UMN) signs. However, whether ALS patients with UMN signs (ALSwUMN) and those without (ALSwoUMN) share similar characteristics and prognoses remains unclear.
Hee‐Jae Jung, E‐nae Cheong, Jungmin So, Heung‐Won Kang, Yangsean Choi, Eun‐Jae Lee, Hyunjin Kim, Young‐Min Lim   +7 more
wiley   +1 more source

A CD26+ tendon stem progenitor cell population contributes to tendon repair and heterotopic ossification

Nature Communications
Inadequate tendon healing and heterotopic bone formation result in substantial pain and disability, yet the specific cells responsible for tendon healing remain uncertain.
Siwen Chen, Yingxin Lin, Hao Yang, Zihao Li, Sifang Li, Dongying Chen, Wenjun Hao, Shuai Zhang, Hua Chao, Jingyu Zhang, Jianru Wang, Zemin Li, Xiang Li, Zhongping Zhan, Hui Liu   +14 more
doaj   +1 more source

Pro-inflammatory activity of long noncoding RNA FOXD2-AS1 in Achilles tendinopathy

Journal of Orthopaedic Surgery and Research, 2023
Achilles tendinopathy is a prevalent clinical problem that plagues athletes and general populations. Achilles tendon healing is a complex process, and so far, there is no successful long-term solution to Achilles tendinopathy in the field of microsurgery
Xiaoting Ke, Wenjie Zhang
doaj   +1 more source

Using Platelet-Rich Plasma to Reverse the Effects of Tendinopathy and Prevent Tendon Re-rupture after Surgery in Athletes: The Search for a Standardized Protocol [PDF]

, 2016
30-50% of all lesions amateur and professional sports players will experience during activity are related to the tendon. Moreover, the incidence of tendinopathy, a precursor to tendon rupture, is much higher in both of these groups due to excessive ...
Patel, Shiv
core   +1 more source