Results 71 to 80 of about 50,665 (217)

Arthroscopic 4-Anchor Double-Pulley Suture-Bridge Repair of Large Rotator Cuff Tear

Arthroscopy Techniques
Currently, suture bridge (SB) is a popular way to treat large rotator cuff tears. However, the restricted number of sutures used for tendon fixation, the knotted medial row, and the excessive number of tendon holes created from suture hook piercing are ...
Peiguan Huang, M.Med., Xiaoxu Wang, M.Med., Yong Fu, M.D., Xiaojun Tang, M.D., Zhihong Xiao, M.D., Zhengmao Li, M.D., Chunrong He, M.D.   +6 more
doaj   +1 more source

ACLY‐Driven Metabolic Reprogramming Promotes Histone Acetylation and Inflammation‐Associated Fibrosis in Chronic Kidney Disease

Advanced Science, EarlyView.
This study reveals a citrate–ACLY–H3K27ac metabolic–epigenetic axis driving inflammatory gene activation and kidney fibrosis, highlighting ACLY inhibition as a potential therapeutic strategy for chronic kidney disease (CKD). ABSTRACT The mechanisms by which metabolic stress drives epigenetic dysregulation and fibrosis in chronic kidney disease (CKD ...
Chunxiu Du, Dhanunjay Mukhi, Lingzhi Li, Chenyu Li, Siyu Pan, Bernhard Dumoulin, Eunji Ha, Lakshmi P Kolligundla, Yanjuan Hou, Jonathan Levinsohn, Chaelin Kang, Konstantin Adrian Klötzer, Junnan Wu, Samer Mohandes, Kathryn E Wellen, Katalin Susztak   +15 more
wiley   +1 more source

Advanced glycation end products impair the repair of injured tendon: a study in rats

BMC Musculoskeletal Disorders
Background The AGEs levels in tissues of diabetics and elderly tend to be higher than in normal individuals. This study aims to determine the effects of AGEs on Achilles tendon repair.
Juan Yang, Jirui He, Ling Yang
doaj   +1 more source

Polylactic acid electrospun membranes coated with chiral hierarchical-structured hydroxyapatite nanoplates promote tendon healing based on a macrophage-homeostatic modulation strategy

Bioactive Materials
Tendon injury is a common and challenging problem in the motor system that lacks an effective treatment, affecting daily activities and lowering the quality of life.
Gang Luo, Juehong Li, Shuai Chen, Zhengqiang Yuan, Ziyang Sun, Tengfei Lou, Zhenyu Chen, Hang Liu, Chao Zhou, Cunyi Fan, Hongjiang Ruan   +10 more
doaj   +1 more source

A Piezo‐Mimetic Ionic Hydrogel Harnessing Joint Motion for Cartilage Repair

Advanced Science, EarlyView.
A piezo‐mimetic ionic hydrogel converts mechanical deformation into bioactive ionic currents via stress‐induced asymmetric ion migration. Coupled with sustained Mg2+ release, this mechano‐electrochemical platform bridges mechanical loading and cellular signaling, enabling load‐adaptive stimulation and enhanced cartilage regeneration. ABSTRACT Articular
Chenyuan Gao, Xinyu Wang, Zhifeng Wu, Xinya Zhang, Xiao Geng, Ti Zhang, Yue Wang, Hongwei Xia, Jun Zhang, Xianbo Qiu, Cuiru Sun, Yingjie Yu, Wenli Dai, Hua Tian, Qing Cai   +14 more
wiley   +1 more source

Biomechanical analysis of single-row anchor, double-row anchor, and single-row knotless tape repair techniques for complete subscapularis tears

JSES Reviews, Reports, and Techniques
: Background: Repair techniques for complete subscapularis (SSC) tendon tears have not been evaluated and compared in detail. The purpose of this study was to evaluate the biomechanical performance of different repair techniques for complete SSC tendon ...
Manuel Waltenspül, MD, Sebastian Kiss, MD, Samy Bouaicha, MD, Lukas Ernstbrunner, MD, PhD, Paul Borbas, MD, Karl Wieser, MD   +5 more
doaj   +1 more source

A Wireless 3D Magneto‐Mechanical Stimulation Platform Drives In Situ Chondrogenic Commitment of Endogenous MSCs

Advanced Science, EarlyView.
An intracellular magneto‐mechanical platform utilizing MSC‐targeted nanomotors is developed. After intra‐articular delivery, these nanomotors target endogenous BMSCs and are actuated within lysosomes to execute trans‐planar rotational‐bouncing motions under a rotating‐fluctuating 3D magnetic field, generating amplified mechanical stimulation.
Zhenguang Li, Li Peng, Laiya Lu, Yingying Wang, Xiaolei Chen, Feng Yin, Cuijun Deng, Yu Cheng   +7 more
wiley   +1 more source

Long-term functional outcomes of augmented primary repair using the peroneus brevis tendon for traumatic Achilles tendon ruptures: a retrospective cohort study

BMC Musculoskeletal Disorders
Background Achilles tendon rupture is increasingly common and may result in significant functional impairment. Intraoperative findings such as frayed tendon ends, poor tendon quality, and larger tendon gaps may compromise the reliability of primary end ...
Duong Binh Tran, Thi Cao, Tu Van Phan
doaj   +1 more source

Revision quadriceps tendon repair: A case series and technique guide to a novel repair

Trauma Case Reports
Introduction: Revision quadriceps tendon repair is a challenging problem. In this four-case series, novel quadriceps tendon revision resulted in improved range of motion and durable repair for patients with recurrent rupture.
Ellen Lutnick, Sophia Puertas, Mark Anders   +2 more
doaj   +1 more source

Biodegradable Zn‐Based Implants: Progress, Challenges, and Pathways toward Clinical Translation

Advanced Science, EarlyView.
Exploring biodegradable Zn‐based implants offers a promising pathway to next‐generation biomedical devices with balanced degradation and biocompatibility. A comprehensive overview of biodegradable Zn‐based implants, covering their biological significance, material design principles, and advanced engineering strategies is provided.
Panfeng Zhao, Zhengquan Wang, Hui Yang, Xiyuan Zhang, Hanyuan Liu, Xiaotong Lu, Xiaocheng Li, Yanyan Liu, Xi Zhao, Wenhao Zhou, Yufeng Zheng   +10 more
wiley   +1 more source