Results 81 to 90 of about 226,465 (363)

Structural Motifs in Soft Fibrous Tissues: Revealing Structure‐Mechanics Relationships in Deformation and Tear Resistance for Biomimetic Material Design

Advanced Healthcare Materials, EarlyView.
This review explores how soft fibrous tissues achieve their remarkable mechanical behavior through recurring structural motifs across multiple length scales. It highlights key advances in mimicking these features using fiber‐reinforced hydrogels and hierarchical composites, offering insights into mechanical compatibility, flaw tolerance, and tear ...
Mirit Sharabi
wiley   +1 more source

Effects of mesenchymal stromal cells versus serum on tendon healing in a controlled experimental trial in an equine model [PDF]

, 2018
Background Mesenchymal stromal cells (MSC) have shown promising results in the treatment of tendinopathy in equine medicine, making this therapeutic approach seem favorable for translation to human medicine.
A Chapel, A De Becker, A Hillmann, A. B. Ahrberg, A. Hillmann, AJ Nixon, AM Carvalho, B Addicott, C. Gittel, C. Horstmeier, C. Josten, CA Bourzac, CS Avella, D Little, D. Berner, DJ Guest, EE Godwin, F Geburek, F Geburek, F Paebst, F Vannini, G. Rossi, H Alfredson, IF Williams, J Burk, J Burk, J Burk, J Kittler, J. Burk, JC Patterson-Kane, K Astanina, K. Winter, L Wang, L Willberg, LE Richardson, LV Schnabel, M Carvalho A de, M Dominici, MW Pfaffl, P Bourin, P Conze, P Sadoghi, R Schäfer, RB Williams, RKW Smith, RKW Smith, RKW Smith, S de Jonge, S de Jonge, S. Schubert, SA Vallance, SG Dakin, T Martinello, U Delling, W Brehm, W. Brehm, Y Yang   +56 more
core   +1 more source

Impact of Fiber Orientation in Electrospun PLA Scaffolds on Fluid Dynamics in a Custom Microfluidic Device

Advanced Healthcare Materials, EarlyView.
Fiber orientation in electrospun scaffolds affects permeability and fluid dynamics in microfluidic devices. Combining experimental data with computational fluid dynamic simulations, we show that aligned fibers enhance flow uniformity, reduce pressure and shear stress variability.
Elisa Capuana, Maria Testa, Chiara Di Marco, Francesco Lopresti, Vincenzo La Carrubba   +4 more
wiley   +1 more source

Comparison of high resolution ultrasonography with clinical findings in patients with ankle pain

Journal of Ultrasonography, 2018
Aim: The aim of this study was to investigate the diagnostic accuracy of high resolution ultrasonography for the assessment of painful ankle joint as compared with the clinical findings.
Kunwarpal Singh, Chuni Lal Thukral, Kamlesh Gupta, Avtar Singh   +3 more
doaj   +1 more source

Microphysiological Systems for Comorbidity Studies: Chronic Kidney Disease and Osteoarthritis

Advanced Healthcare Materials, EarlyView.
This review highlights the potential of organ‐on‐a‐chip systems for studying comorbidities, using chronic kidney disease (CKD) and osteoarthritis (OA) as examples. It summarizes recent advances in kidney‐on‐a‐chip and joint‐on‐a‐chip models and discusses their current and potential application in investigating CKD, OA, and CKD‐OA comorbidity, aiming to
Mingying Han, Weiping Lin, Yuanxiong Cao, Patricia Murray, Bettina Wilm, Stephen J McWilliam, Jude Curran, Ruoxiao Xie   +7 more
wiley   +1 more source

Conditioned Media from Mechanically Stimulated Macrophages Upregulate Osteogenic Genes in Human Mesenchymal Stromal Cells

Advanced Healthcare Materials, EarlyView.
Bone fracture healing is a complex, timely orchestrated scenario involving multiple cell types and a plethora of cytokines and regulatory factors. To gain further insight, an in vitro model to a) study macrophage polarization under mechanical load in a fibrin hydrogel and b) subsequently assess the effect of conditioned media derived from macrophages ...
Anne Géraldine Guex, Ursula Menzel, Yann Ladner, Angela R. Armiento, Martin J. Stoddart   +4 more
wiley   +1 more source

Therapeutic Implants: Mechanobiologic Enhancement of Osteogenic, Angiogenic, and Myogenic Responses in Human Mesenchymal Stem Cells on 3D‐Printed Titanium Truss

Advanced Healthcare Materials, EarlyView.
This study investigates a synergistic effect between 3D‐printed surface features and mechanical micro‐strain in enhancing the osteogenic, angiogenic, and myogenic responses of human mesenchymal stem cells (hMSCs). Load‐induced mechanotransduction, facilitated by the implant's architectural design, significantly amplifies hMSC differentiation.
Se‐Hwan Lee, Ali Kiapour, Brendan D. Stoeckl, Ellen Y. Zhang, Matthew R. Begley, Jarod Oldham, Lewis Harrison, Jessee Hunt, Robert L. Mauck, Su Chin Heo   +9 more
wiley   +1 more source

Patellar Tendon Morphology in Trans-tibial Amputees Utilizing a Prosthesis with a Patellar-tendon- Bearing Feature [PDF]

, 2019
A patellar-tendon-bearing (PTB) bar is a common design feature used in the socket of trans-tibial prostheses to place load on the pressure-tolerant tissue.
Bashford, Gregory, Chang, Yu-Jen, Harty, Michelle, Ho, Kai-Yu, Kellogg, Jessica, Lee, Szu-Ping, Teter, Kelly   +6 more
core   +4 more sources

A Comprehensive Review of Clinical Studies on Bacterial Cellulose: From the Earliest Uses to Contemporary Innovations

Advanced Healthcare Materials, EarlyView.
Bacterial cellulose has undergone a transformative journey from early applications to its role in advanced regenerative medicine. The review has a pedagogical ambition, offering clear pathways for future research and clinical adoption. Harmonizing regulatory standards and conducting larger, well‐designed clinical trials with standardized endpoints will
Thomas Meslier, Justin Christopher D'Antin, Gemma Julio, Anna Roig   +3 more
wiley   +1 more source

Histological evidence for a supraspinous ligament in sauropod dinosaurs [PDF]

, 2015
Supraspinous ossified rods have been reported in the sacra of some derived sauropod dinosaurs. Although different hypotheses have been proposed to explain the origin ofthis structure, histological evidence has never been provided to support or reject any
Abdalla O, Abdel Meguid EM, Barreto C, Bonaparte JF, Bonaparte JF, Campos D, Casal GA, Casal GA, Cerda IA, Cerda IA, Chinsamy A, Chinsamy-Turan A, Francillon-Vieillot H, García RA, Giménez O, Gomani M, Güner A, Hamdam TA, Hatcher JB, Henderson D, Heylings DJA, Horner JR, Janensch W, Janensch W, Kellner AWA, Mcintosh JS, Morocutti M, Novas FE, Osborn HF, Powell JE, Powell JE, Powell JE, Reid REH, Sandqvist AV, Strocchi R, Yayama T, You H-L, Zhang Y   +37 more
core   +2 more sources