PD-L1 Status in Tenosynovial Giant Cell Tumors [PDF]
Medicina, 2022 Background and Objectives: Tenosynovial giant cell tumors (TSGCTs) are benign soft tissue tumors that are divided into localized- and diffuse-type tumors, according to the World Health Organization classification of soft tissue tumours.
Tulay Zenginkinet +8 more
doaj +7 more sources
Expanding the molecular spectrum of tenosynovial giant cell tumors [PDF]
Frontiers in Oncology, 2022 BackgroundWhile great advances in clinical and pathological description of tenosynovial giant cell tumors (TGCT) have been made, TGCT molecular heterogeneity represents an ongoing challenge.
Thibault Gauduchon +16 more
doaj +6 more sources
T2-star (T2*)-weighted magnetic resonance imaging of tenosynovial giant cell tumors [PDF]
European Journal of Radiology Open, 2023 Purpose: Tenosynovial giant cell tumors (TSGCTs) are benign but aggressive lesions, and the treatment is resection. A low to intermediate signal intensity on both T1- and T2-weighted images of magnetic resonance imaging (MRI) is characteristic, which is ...
Akio Sakamoto +2 more
doaj +5 more sources
Tenosynovial giant cell tumor in an unusual localization
Acta Orthopaedica et Traumatologica Turcica, 2020 Tenosynovial giant cell tumors are benign tumors that are often localized on the palmar sites of the hand. The involvement of large joints such as the knee and ankle are rare. We present an 18-year-old male patient referred to the orthopedics clinic with
Esin Atik +3 more
doaj +6 more sources
Interactions in CSF1-Driven Tenosynovial Giant Cell Tumors. [PDF]
Clin Cancer Res, 2022 Abstract The majority of cells in Tenosynovial Giant Cell Tumor (TGCT) are macrophages responding to CSF1 that is overproduced by a small number of neoplastic cells with a chromosomal translocation involving the CSF1 gene.
van IJzendoorn DGP +15 more
europepmc +6 more sources
Tenosynovial giant cell tumor of the distal tibiofibular joint [PDF]
Radiology Case Reports, 2021 Tenosynovial giant cell tumors are extremely rare tumors with highly nonspecific symptoms. This benign but aggressive disease has a slow course of progression; however, it can ultimately lead to irreversible damage to a joint.
Stephanie D. Zarate, PA-C +2 more
doaj +5 more sources
Burden of Illness Associated with Tenosynovial Giant Cell Tumors. [PDF]
Clin Ther, 2018 Little is known about the burden of illness in patients with tenosynovial giant cell tumors (TGCT), which are rare, typically benign, lesions of the synovial tissue including giant cell tumor of the tendon sheath (GCT-TS) and pigmented villonodular synovitis (PVNS).
Burton TM +4 more
europepmc +5 more sources
Localized tenosynovial giant cell tumor in children
Journal of Children's Orthopaedics, 2023 Background: To investigate the clinical characteristics and surgical efficacy of localized tenosynovial giant cell tumors in children. Methods: The clinical data, surgery, and follow-up results of 17 children with localized tenosynovial giant cell tumors
Xifeng Du +3 more
doaj +3 more sources
Recent advances in immunohistochemical and molecular profiling for differential diagnosis between giant cell-rich lesions and tenosynovial giant cell tumors [PDF]
Frontiers in OncologyJiro Ichikawa +6 more
doaj +4 more sources
Tenosynovial Giant Cell Tumors in the Hand and Foot. [PDF]
CureusGiant cell tumor of the tendon sheath (GCTTS) is one of the most common benign, slow-growing soft tissue tumors of the hand and foot. This study aimed to evaluate the anatomic distribution of the GCTTS and correlate the surgical treatment with clinical outcomes and recurrence rates.In this retrospective study, a total of 78 cases of GCTTS of the hand ...
Stefanou N +5 more
europepmc +3 more sources