Interplay between RNA‐protein interactions and RNA structures in gene regulation
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko +2 more
wiley +1 more source
Friction-driven scission: How nonlocal mechanisms contribute to membrane fission across domains of life. [PDF]
Landajuela A +4 more
europepmc +1 more source
Cinématographies périphériques dans le système global de distribution: tensions structurelles
Josetxo Cerdán Los Arcos
openalex +2 more sources
Molecular Tension Probes to Quantify Cell-Generated Mechanical Forces
Kyung Yup Baek, Seohyun Kim, Hye Ran Koh
openalex +2 more sources
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama +7 more
wiley +1 more source
Spatiotemporal Regulation of Ligand Trafficking and TLR9 Activation by PIEZO1 in Human Plasmacytoid Dendritic Cells. [PDF]
Pattanayak S +11 more
europepmc +1 more source
A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley +1 more source
Optimization and performance evaluation of a fully biodegradable dust suppressant with ternary synergistic effect. [PDF]
Qi C +5 more
europepmc +1 more source
HSP70 governs permeability and mechanotransduction in primary human endothelial cells
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez +5 more
wiley +1 more source
Effect of psidium guajava fruit suspension on periodontium following orthodontic tooth movement in wistar rats-histologic findings. [PDF]
Aldeeri A +3 more
europepmc +1 more source

