Results 241 to 250 of about 3,568,014 (331)

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Management of strangulated, perforated gastrothorax with resultant tension pneumothorax secondary to an iatrogenic diaphragmatic hernia: a case report. [PDF]

J Surg Case Rep
Naim A, Sarkar A.
europepmc   +1 more source

Influence of low oxygen tensions on macrophage polarization

, 2012
María M. Escribese, Mateo Casas, Ángel L. Corbí   +2 more
openalex   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Tension-Dominant Orthodontic Loading and Buccal Periodontal Phenotype Preservation: An Integrative Mechanobiological Model Supported by FEM and a Proof-of-Concept CBCT. [PDF]

J Funct Biomater
Kuc AE, Kotuła J, Sybilski K, Saternus S, Małachowski J, Kuc N, Hajduk G, Lis J, Kawala B, Sarul M, Sulewska M.   +10 more
europepmc   +1 more source

Elastocapillarity: when Surface Tension Deforms Elastic Solids

, 2018
J. Bico, É. Reyssat, B. Roman
semanticscholar   +1 more source

ALVEOLAR-ARTERIAL OXYGEN TENSION DIFFERENCES IN ANAESTHETIZED HORSES

, 1968
L.W. Hall, J. R. Gillespie, W. S. Tyler
openalex   +1 more source

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source

Bimodal Mechanical Response of Membrane Necks: Implications for the Nuclear Envelope. [PDF]

ACS Nano
Geiger BJ, Pezeshkian W.
europepmc   +1 more source

Study on the bearing-deformation characteristics and optimizing design of tension-compression composite anchor bolts in earthen heritage sites

Donghua Wang, Kaiyu Cui, Ya Zhe Xing, Xiaohu Shen, Yao Wang, Kai Cui   +5 more
openalex   +1 more source