Results 221 to 230 of about 1,582,483 (298)

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Acupotomy Activates PI3K/Akt Signaling Pathway Mediated by FGF7,10/KDR Axis to Regulate Apoptosis. [PDF]

J Pain Res
Qian JM, Wang XL, Fang T, Liu L, Liu FS, Zhao XL, Tumurbaatar K.   +6 more
europepmc   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Delayed Signaling in Mitotic Checkpoints: Biological Mechanisms and Modeling Perspectives. [PDF]

Biology (Basel)
Ibrahim B.
europepmc   +1 more source

eArly phySical therApy Program for PatelloFemoral Pain (ASAP-PFP trial): protocol for a triple-blinded, superiority, parallel-group, multicentre trial. [PDF]

BMJ Open Sport Exerc Med
Waiteman MC, Ferreira BS, Glaviano NR, Bazett-Jones DM, Van Cant J, Farraj M, Briani R, De Azevedo FM.   +7 more
europepmc   +1 more source

Predicting porosity in composite high-pressure hydrogen vessels using augmented fuzzy cognitive AI and manufacturing process parameters. [PDF]

Sci Rep
Achour L, Zalila Z, Aboura Z, Lorentz B, Ruggi D, Khellil K.   +5 more
europepmc   +1 more source

Real-world management patterns and outcomes in normal-tension glaucoma. [PDF]

Indian J Ophthalmol
Rao A, Ray P.
europepmc   +1 more source

Immediate effects of kinesiology taping on proprioception and functional performance in collegiate athletes with chronic ankle instability: evidence from event-related potentials. [PDF]

BMC Sports Sci Med Rehabil
Chang CL, Lin HY, Tseng YT, Pan CY, Chen FC, Tsai CL.   +5 more
europepmc   +1 more source