Finsler geometry on higher order tensor fields and applications to high angular resolution diffusion imaging. [PDF]
, 2009 We study 3D-multidirectional images, using Finsler geometry. The application considered here is in medical image analysis, specifically in High Angular Resolution Diffusion Imaging (HARDI) (Tuch et al. in Magn. Reson. Med.
Florack, L.M.J. +9 more
core +2 more sources
Spline- and tensor-based signal reconstruction : from structure analysis to high-performance algorithms to multiplatform implementations and medical applications [PDF]
, 2015 The problem of signal reconstruction is of fundamental practical value for many applications associated with the field of signal and image processing.
Morozov, Oleksii
core +1 more source
Varying Coefficient Tensor Models for Brain Imaging [PDF]
, 2005 We revisit a multidimensional varying-coefficient model (VCM), by allowing regressor coefficients to vary smoothly in more than one dimension, thereby extending the VCM of Hastie and Tibshirani.
Marx, Brian D. +2 more
core +1 more source
Impact of the control for corrupted diffusion tensor imaging data in comparisons at the group level : an application in Huntington disease [PDF]
, 2014 This work was supported by the European Union under the Seventh Framework programme– PADDINGTON Project, Grant Agreement No. 261358, and the European Huntington’s Disease Network (EHDN), project 070 – PADDINGTON.Background: Corrupted gradient directions (
Landwehrmeyer, G.B. +13 more
core +1 more source
Dilation theory for rank two graph algebras. [PDF]
, 2010 An analysis is given of $*$-representations of rank 2 single vertex graphs. We develop dilation theory for the non-selfadjoint algebras $\A_\theta$ and $\A_u$ which are associated with the commutation relation permutation $\theta$ of a 2-graph and, more ...
Yang, Dilian +2 more
core +4 more sources
FMRI guided DTI at the grey-white matter interface : with application to a connectivity analysis of the default mode network in Urbach-Wiethe disease [PDF]
, 2011 Includes abstract.Includes bibliographical references.The cerebral cortex is composed of a thin layer of Grey Matter (GM), functionally subdivided into discrete regions which are connected in a large scale network via White Matter (WM) tracts. With fMRI (
Baasch, Roland
core +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
FEBS Open Bio, EarlyView.In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source