Results 11 to 20 of about 86,819 (232)

Gene dosage compensation: Origins, criteria to identify compensated genes, and mechanisms including sensor loops as an emerging systems‐level property in cancer

Cancer Medicine, Volume 12, Issue 24, Page 22130-22155, December 2023., 2023
Abstract The gene dosage compensation hypothesis presents a mechanism through which the expression of certain genes is modulated to compensate for differences in the dose of genes when additional chromosomes are present. It is one of the means through which cancer cells actively cope with the potential damaging effects of aneuploidy, a hallmark of most
Diana M. Bravo‐Estupiñan, Karol Aguilar‐Guerrero, Steve Quirós, Man‐Sai Acón, Christian Marín‐Müller, Miguel Ibáñez‐Hernández, Rodrigo A. Mora‐Rodríguez   +6 more
wiley   +1 more source

Using Artificial Intelligence to Develop a Multivariate Model with a Machine Learning Model to Predict Complications in Mexican Diabetic Patients without Arterial Hypertension (National Nested Case‐Control Study): Metformin and Elevated Normal Blood Pressure Are Risk Factors, and Obesity Is Protective

Journal of Diabetes Research, Volume 2023, Issue 1, 2023., 2023
Diabetes mellitus is a disease with no cure that can cause complications and even death. Moreover, over time, it will lead to chronic complications. Predictive models have been used to identify people with a tendency to develop diabetes mellitus.
Sergio A. Zaizar-Fregoso, Agustin Lara-Esqueda, Carlos M. Hernández-Suarez, Josuel Delgado-Enciso, Arturo Garcia-Nevares, Luis M. Canseco-Avila, Jose Guzman-Esquivel, Iram P. Rodriguez-Sanchez, Margarita L. Martinez-Fierro, Gabriel Ceja-Espiritu, Hector Ochoa-Díaz-Lopez, Francisco Espinoza-Gomez, Iyari Sanchez-Diaz, Ivan Delgado-Enciso, Guanghong Jia   +14 more
wiley   +1 more source

Systemic Administration of Neutral Electrolyzed Saline as a Novel Treatment for Rheumatoid Arthritis Reduces Mechanical and Inflammatory Damage to the Joints: Preclinical Evaluation in Mice

Evidence-Based Complementary and Alternative Medicine, Volume 2022, Issue 1, 2022., 2022
Rheumatoid arthritis is globally present in about 1% of the population. This autoinflammatory disease modifies the connective tissue, causing pain and inflammation of the joints. Over time, it causes the loss of joint cartilage and bone mass, decreasing the patient's quality of life.
Sergio A Zaizar-Fregoso, Brenda A Paz-Michel, Alejandrina Rodriguez-Hernandez, Juan Paz-Garcia, Nomely S. Aurelien-Cabezas, Daniel Tiburcio-Jimenez, Valery Melnikov, Efren Murillo-Zamora, Osiris G Delgado-Enciso, Ariana Cabrera-Licona, José Guzman-Esquivel, Carlos E Barajas-Saucedo, Iram P Rodriguez-Sanchez, Margarita L Martinez-Fierro, Norma A Moy-López, Agustin Lara-Esqueda, Jorge Guzman-Muñiz, Marina Delgado-Machuca, Ivan Delgado-Enciso, Xing Li   +19 more
wiley   +1 more source

Similar Inflammatory Adaptation in Women following 10 Weeks of Two Equalized Resistance Training with Different Muscle Action Duration

BioMed Research International, Volume 2022, Issue 1, 2022., 2022
This study is aimed at evaluating the profile of inflammatory markers and components of redox regulation in untrained women after 10 weeks of resistance training using equalized protocols but different muscle action duration (MAD). Twenty‐two women underwent progressive resistance training exercising the knee extensor muscles for 10 weeks—3x/week, with
Kelerson Mauro de Castro Pinto, Rodrigo César Ribeiro Diniz, Frank Douglas Tourino, Lucas Túlio de Lacerda, Eduardo Bearzoti, Karine Beatriz Costa, Débora Maria Soares de Souza, Fernando Vitor Lima, Etel Rocha-Vieira, Mauro Heleno Chagas, Andre Talvani, Chuan Ye   +11 more
wiley   +1 more source

Treatment of equine sarcoids using recombinant poxviruses expressing feline interleukin‐2

Veterinary Dermatology, Volume 32, Issue 3, Page 283-e77, June 2021., 2021
Background – Interleukin (IL)‐2 stimulates antitumour immunity and is successfully used for the treatment of different neoplasias. Hypothesis/Objectives –Canarypox virus locally expressing feline IL‐2 is safe and can be used to treat equine sarcoids. Conclusions –Treatment of equine sarcoids with recombinant canarypox virus expressing feline IL‐2 seems
Johanna Loschelder‐Ostrowski, Judith Christine Winter, Roswitha Merle, Robert Klopfleisch, Heidrun Gehlen   +4 more
wiley   +1 more source

Una perspectiva raciolingüística desde el Reino Unido

, 2023
Journal of Sociolinguistics, Volume 27, Issue 5, Page 478-482, November 2023.
Ian Cushing
wiley   +1 more source

Efecto de la terapia biológica en las concentraciones de DKK1 y esclerostina, riesgo cardiovascular y metabolismo óseo en pacientes con artritis reumatoide

Revista de Osteoporosis y Metabolismo Mineral, 2018
Introducción: Estudios previos han relacionado la vía Wnt con la alteración del metabolismo óseo y la patología cardiovascular. Así mismo, el control de la inflamación con terapia biológica tiene un efecto positivo sobre la densidad mineral ósea (DMO) y ...
Palma-Sánchez D, Haro-Martínez AC, Gallardo Muñoz I, Portero de la Torre M, García-Fontana B, Reyes-García R   +5 more
doaj   +1 more source

[Translated article] Practical Update of the Recommendations Published by the Psoriasis Group of the Spanish Academy of Dermatology and Venereology (GPs) on the Treatment of Psoriasis with Biologic Therapy. Part 1. Concepts and General Management of Psoriasis With Biologic Therapy

Actas Dermo-Sifiliográficas, 2022
Background and objectives: A new, updated AEDV Psoriasis Group (GPs) consensus document on the treatment of moderate to severe psoriasis was needed owing to the approval, in recent years, of a large number of new drugs and changes in the treatment ...
J.M. Carrascosa, L. Puig, I. Belinchón Romero, L. Salgado-Boquete, E. del Alcázar, J.J. Andrés Lencina, D. Moreno, P. de la Cueva   +7 more
doaj   +1 more source

Inmunogenicidad en terapia biológica. Implicaciones en Dermatología

Actas Dermo-sifiliográficas, 2013
J.M. Carrascosa
exaly   +2 more sources

Decrease in primary but not in secondary abdominal surgery for Crohn's disease: nationwide cohort study, 1990–2014

BJS (British Journal of Surgery), Volume 107, Issue 11, Page 1529-1538, October 2020., 2020
In a Swedish population‐based database, the cumulative incidence of a first abdominal surgical procedure after a diagnosis of Crohn's disease has decreased by two‐thirds over the past 25 years. The risk of repeat abdominal surgery has not decreased since the introduction of biologicals. Ileocaecal resection remained the most common procedure during the
T. D. Kalman, Å. H. Everhov, C. Nordenvall, M. C. Sachs, J. Halfvarson, A. Ekbom, J. F. Ludvigsson, P. Myrelid, O. Olén   +8 more
wiley   +1 more source