Results 11 to 20 of about 3,988 (127)

Sex‐ and APOE‐specific genetic risk factors for late‐onset Alzheimer's disease: Evidence from gene–gene interaction of longevity‐related loci

Aging Cell, Volume 22, Issue 9, September 2023., 2023
Genetic studies over the last few years, have changed the perception of late‐onset Alzheimer's disease (LOAD), highlighting its polygenic nature with multiple susceptibility genetic loci. We applied a multidimensional reduction approach to detect gene–gene interactions affecting LOAD by testing variants harbored by genes previously investigated in ...
Serena Dato, Francesco De Rango, Paolina Crocco, Stefano Pallotti, Michael E. Belloy, Yann Le Guen, Michael D. Greicius, Giuseppe Passarino, Giuseppina Rose, Valerio Napolioni   +9 more
wiley   +1 more source

The Ethical Triage Dilemma: Who Should Receive Medical Care First; Is This the Right Question?

Ratio Juris, Volume 36, Issue 2, Page 178-190, June 2023., 2023
Abstract In 2020, with the outbreak of the COVID‐19 pandemic, academics and scientists began to question the triage criteria for allocating insufficient healthcare resources, trying to ethically justify the answer to the question, Who should receive medical care first?
Alessandro Ferrara
wiley   +1 more source

Evaluation of the Antitumor Effects of Platinum‐Based [Pt(η1‐C2H4‐OR)(DMSO)(phen)]+ (R = Me, Et) Cationic Organometallic Complexes on Chemoresistant Pancreatic Cancer Cell Lines

Bioinorganic Chemistry and Applications, Volume 2023, Issue 1, 2023., 2023
Pancreatic cancer is one of the most lethal malignancies with an increasing incidence and a high mortality rate, due to its rapid progression, invasiveness, and resistance to anticancer therapies. In this work, we evaluated the antiproliferative and antimigratory activities of the two organometallic compounds, [Pt(η1‐C2H4‐OMe)(DMSO)(phen)]Cl (1) and ...
Erika Stefàno, Luca Giulio Cossa, Federica De Castro, Erik De Luca, Viviana Vergaro, Giulia My, Gianluca Rovito, Danilo Migoni, Antonella Muscella, Santo Marsigliante, Michele Benedetti, Francesco Paolo Fanizzi, Giovanni Natile   +12 more
wiley   +1 more source

Cardioprotective Effects of Solidago microglossa DC. in Nicotine‐Treated Hypertensive Rats

Evidence-Based Complementary and Alternative Medicine, Volume 2023, Issue 1, 2023., 2023
Solidago microglossa DC. (Asteraceae), “arnica brasileira,” is a Brazilian species popularly used to treat hypertension or renal ailments. This study investigated the cardioprotective effects of standardized S. microglossa extract (EESM) in nicotine‐treated spontaneously hypertensive rats (SHRs).
Katiana Simões Lopes, Aline Aparecida Macedo Marques, Karyne Garcia Tafarelo Moreno, Ariany Carvalho dos Santos, Roosevelt Isaías Carvalho Souza, Emerson Luiz Botelho Lourenço, Rodrigo Juliano Oliveira, Roberto da Silva Gomes, Francislaine Aparecida dos Reis Lívero, Arquimedes Gasparotto Junior, Ana L. Cia Abreu Silva   +10 more
wiley   +1 more source

Small Extracellular Vesicles Secreted by Nigrostriatal Astrocytes Rescue Cell Death and Preserve Mitochondrial Function in Parkinson's Disease

Advanced Healthcare Materials, Volume 11, Issue 20, October 19, 2022., 2022
Astrocytes from the main brain regions affected by Parkinson's disease (PD) secrete different levels of extracellular vesicles (EVs). CCL3‐EVs better protect neurons from apoptosis and only ventral midbrain‐derived EVs ameliorate ATP production in neurotoxin‐injured neurons.
Loredana Leggio, Francesca L'Episcopo, Andrea Magrì, María José Ulloa‐Navas, Greta Paternò, Silvia Vivarelli, Carlos A. P. Bastos, Cataldo Tirolo, Nunzio Testa, Salvatore Caniglia, Pierpaolo Risiglione, Fabrizio Pappalardo, Alessandro Serra, Patricia García‐Tárraga, Nuno Faria, Jonathan J. Powell, Luca Peruzzotti‐Jametti, Stefano Pluchino, José Manuel García‐Verdugo, Angela Messina, Bianca Marchetti, Nunzio Iraci   +21 more
wiley   +1 more source

UEG Week 2025 Poster Presentations [PDF]

United European Gastroenterol J
United European Gastroenterology Journal, Volume 13, Issue S8, Page S803-S1476, October 2025.
europepmc   +2 more sources

Transpupillary thermotherapy for malignant choroidal melanoma [PDF]

, 2001
Purpose: Several methods have been used for treatment of choroidal melanoma. The purpose of this preliminary paper is to evaluate the effectiveness of transpupillary thermo- therapy (TTT) as a primary treatment of small choroidal melanomas. Methods: This
Chojniak, Martha M. Motomo, Erwenne, Clélia Maria, Guia, Tércio, Uno, Fausto   +3 more
core   +3 more sources

Análise dos efeitos da terapia por ultra-som 3 MHz sobre a concentração sangüí­nea de lipí­deos de ratas Wistar [PDF]

Fisioterapia Brasil, 2017
O objetivo deste trabalho foi verificar as concentrações plasmáticas de colesterol, triglicerí­deos e lipí­deos totais após terapia por ultra-som pulsado de 3 MHz, em ratas Wistar. Asratas foram divididas em grupo experimental e placebo e subdivididas conforme o tempo de retirada do sangue.
openaire   +1 more source

Low-power laser therapy accelerates peripheral nerves' regeneration [PDF]

, 2008
Há evidências de que a terapia com o laser pode estimular a regeneração de nervos e esta hipótese foi testada em ratos. Uma lesão por esmagamento controlado foi produzida no nervo isquiático de 20 ratos Wistar, metade dos quais foram submetidos a ...
BARBIERI, Cláudio Henrique, ENDO, Cristina, FASAN, Valéria S., MAZZER, Nilton   +3 more
core   +2 more sources

Usefulness of neck ultrasonography in the follow-up of patients with differentiated thyroid cancer [PDF]

, 2007
Neck ultrasonography (US) is recommended for the assessment of all patients with thyroid carcinoma after initial therapy, since even low-risk patients with undetectable stimulated thyroglobulin (Tg) may present cervical metastases.
Biscolla, Rosa Paula M., Maciel, Rui Monteiro de Barros, Purisch, Saulo, Rosário, Pedro W., Tavares Júnior, Wilson C.   +4 more
core   +3 more sources