Cancer-associated TERT promoter mutations abrogate telomerase silencing. [PDF]
, 2015 Mutations in the human telomerase reverse transcriptase (TERT) promoter are the most frequent non-coding mutations in cancer, but their molecular mechanism in tumorigenesis has not been established.
Boyle, John +5 more
core +1 more source
Analysis of Human Uniparental Embryonic Stem Cells Reveals New Putative Imprinted Loci
Cell Proliferation, EarlyView.To identify novel imprinted genes, parthenogenetic, androgenetic and biparental human embryonic stem cells and their differentiated neural progenitors were analysed by methylome and transcriptome profiling. This approach uncovered 12 putative novel imprinted genes, including a clustered region on chromosome 19, expanding the current catalogue of ...
Shay Kinreich, Nissim Benvenisty
wiley +1 more source
Testicular mass frozen section examination: Pathological insights and diagnostic accuracy
Histopathology, EarlyView.Frozen section examination on testicular excisional biopsy is accurate and can help avoid unnecessary radical orchidectomy. A very high concordance rate between frozen section diagnosis and permanent diagnosis was obtained with no false negatives.
Roselyne Choiniere +3 more
wiley +1 more source
Ovarectomy despite Negative Imaging in Anti-NMDA Receptor Encephalitis: Effective Even Late
Case Reports in Neurological Medicine, 2013 Anti-NMDA receptor (NMDAR) encephalitis is an autoimmune antibody-mediated neuropsychiatric disorder. The disorder is known to be associated with ovarian teratoma and predominantly affects young women. Here, we report the case of a 34-year-old woman with
Anna-Lena Boeck +6 more
doaj +1 more source
Recurrence of retroperitoneal mature cystic teratoma in an adult: A case report
Radiology Case Reports, 2019 Mature cystic teratoma is one of the most common tumors of the ovaries, testis, mediastinum, and retroperitoneum; however, secondary retroperitoneum lesions are rare entities in adults.
Van Trung Hoang +3 more
doaj +1 more source
Clinicopathologic Analysis of Sarcomas in the Oral and Maxillofacial Region: A Systematic Review
Oral Diseases, EarlyView.ABSTRACT Objective This study aimed to systematically review primary sarcomas in the oral and maxillofacial region, focusing on patient demographics and sarcoma‐specific characteristics, including clinical presentation, histopathology, treatment approaches, outcomes, and survival rates.
Iara Vieira Ferreira +7 more
wiley +1 more source
Successful Multimodal Treatment of Intracranial Growing Teratoma Syndrome with Malignant Features
Current OncologyMolecular analysis of the growing teratoma syndrome has not been extensively studied. Here, we report a 14-year-old boy with a growing mass during treatment for a mixed germ cell tumor of the pineal region.
Daiken Satake +20 more
doaj +1 more source
Currarino syndrome with two synchronous presacral teratomas
Journal of Pediatric Surgery Case Reports, 2018 Currarino syndrome is rare and consists of an anorectal malformation, a sacrococcygeal bony defect and a presacral mass. Each feature is present to a variable degree in affected individuals. The syndrome develops as a result of a heterozygous mutation in
Timothy A. Little +6 more
doaj +1 more source
Meningothelial Meningioma Component in a Prepubertal Testicular Teratoma
Case Reports in Pathology, 2020 Teratomas are nonseminomatous germ cell tumors composed of elements derived from more than one germinal layers (endoderm, mesoderm, and ectoderm). Malignant transformation of teratoma in the testis is well known; however, benign somatic neoplasm arising ...
Ruchi Sinha +3 more
doaj +1 more source