Results 121 to 130 of about 62,543 (254)

Extracranial, Extragonadal Germ Cell Tumors: A Multicenter Australian Case Series

Asia-Pacific Journal of Clinical Oncology, Volume 22, Issue 3, Page 404-410, June 2026.
Extragonadal germ cell tumors (EGCTs) are rare, with limited prospective data to guide treatment or inform prognosis. Incidence and treatment patterns of EGCT in Australia reflect international data and practices. Compared to testicular primaries, the prognosis of EGCT is poor, especially for primary mediastinal non‐seminoma.
Kar Ven Cavan Chow, Ciara Conduit, Sophie O'Haire, Anna Kuchel, Shirley Wong, Peter Grimison, Andrew Weickhardt, Ganes Pranavan, James Lynam, Patricia Bastick, Jeffrey Goh, Shomik Sengupta, Annabel Smith, Elizabeth Liow, David Campbell, Ming Wong, Kristina Zlatic, Peter Gibbs, Ben Tran, Chun Loo Gan   +19 more
wiley   +1 more source

Different Immune Cells Modified With Chimeric Antigen Receptors Are Being Applied to Ovarian Cancer: Which Is the Most Effective?

Cancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Ovarian Cancer (OC), the deadliest gynecological malignancy, poses a major therapeutic challenge in advanced stages owing to its high recurrence rate and metastatic potential. In this regard, it is noteworthy that immunotherapy has recently gained significant attention in OC treatment, a phenomenon attributable to notable advances in over‐the ...
Liying Wang, Yisen Cao, Yuan Ren, Yuhang Zhang, Liang Wang   +4 more
wiley   +1 more source

Congenital Granular Cell Epulis in a Newborn: Diagnostic and Surgical Challenges in a Resource‐Limited Setting—A Case Report

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Congenital granular cell epulis (CGCE) is a rare benign tumor of the neonatal gingiva, with fewer than 250 cases reported worldwide. It presents most commonly as a pedunculated mass arising from the maxillary alveolar ridge and may interfere with feeding or, rarely, respiration.
Abdisalam Ismail Hassan, Aweis Abdullahi Sheikh, Balqiz Mohamed Kulle, Eid Mohamed Jama, Fardowso Ali Mohamud, Ahmed Muhammad Bashir   +5 more
wiley   +1 more source

Giant Mediastinal Teratoma in a Child: A Case Report With a Brief Review of the Literature

Clinical Case Reports, Volume 14, Issue 5, May 2026.
Contrast‐enhanced axial chest CT showing a large, well‐circumscribed mediastinal mass measuring approximately 15.9 × 14.1 cm (maximum axial dimensions). The lesion is predominantly of fluid attenuation, occupies nearly the entire left hemithorax, and produces marked rightward deviation of the mediastinum, compression of the contralateral lung ...
Urías Hernandez Lopez, Pastor Thomas Olivares, Alex Fernández Arrieta, Juan Correa Palacio, Aura Guevara Díaz, Ana Guerra Urquijo   +5 more
wiley   +1 more source

Genetically engineered human cortical spheroid models of tuberous sclerosis. [PDF]

, 2018
Tuberous sclerosis complex (TSC) is a multisystem developmental disorder caused by mutations in the TSC1 or TSC2 genes, whose protein products are negative regulators of mechanistic target of rapamycin complex 1 signaling. Hallmark pathologies of TSC are
Bateup, Helen, Blair, John, Hockemeyer, Dirk   +2 more
core   +1 more source

Development of a High‐Sensitivity Electrochemical Biosensor for Domoic Acid and Its Cellular Impact on Human Stem and Neuron‐Like Cells

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
Integrated workflow of domoic acid (DA) detection in seafood using a high‐sensitivity electrochemical biosensor and subsequent evaluation of DA‐induced cellular responses. (A) DA monitoring in seafood: Marine samples (European anchovy and mussels from the Marmara and Black Sea) were collected, extracted using a 1:1 methanol/water mixture, and analyzed ...
Emilia Qomi Ekenel, Yucel Koc, Burcugul Altug, Merve Nur Soykan, Bahar Demir Cevizlidere, Sibel Gunes Bagis, Onur Uysal, Tugba Semerci Sevimli, Murat Sevimli, Ayla Eker Sariboyaci, Huseyin Avci   +10 more
wiley   +1 more source

Subsequent ovarian yolk sac tumor after operation of ovarian mature teratoma: a case report and review of the literature

Frontiers in Oncology
Ovarian mature teratoma represents a benign ovarian tumor, while ovarian yolk sac tumor (YST, endodermal sinus tumor) is a rare malignant tumor predominantly affecting young women, often associated with a grim prognosis post-metastasis.
Shuqing Li, Juan Peng, Juan Peng, Yajun Zhang, Dongxia Liu, Lei Li, Manman Nai   +6 more
doaj   +1 more source

Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome

Pediatric Blood &Cancer, Volume 73, Issue 6, June 2026.
Nicholas A. Borja, Anuja Sule, Katie Ann McMullen, Aditi Dhir, Matthew D. Hall, Heather J. McCrea, Sakir Humayun Gultekin, Mustafa Tekin, Bradley Gampel   +8 more
wiley   +1 more source

Clinical Features of Malignant Ovarian Germ Cell Tumors According to Demographic and Pathologic Characteristics

Health Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Aims Malignant ovarian germ cell tumors (MOGCTs) are aggressive cancers affecting mainly young women, in whom fertility preservation is important. Diagnosis is often delayed because early symptoms are non‐specific, leading to advanced disease or emergency surgery that may limit optimal staging and fertility‐sparing treatment. As
Jila Agah, Elham Navipour, Setareh Akhavan, Somaye Norouzi   +3 more
wiley   +1 more source

Bilateral Testicular Tumors Recurred 5 Years After Surgery for an Extragonadal Germ Cell Tumor: Case Report

IJU Case Reports, Volume 9, Issue 3, May 2026.
ABSTRACT Introduction Extragonadal germ cell tumors (EGCT) account for approximately 3%–7% of all germ cell tumors. Metachronous testicular tumors develop in 5%–7% of patients after EGCT treatment; however, bilateral testicular tumors have not been reported. Case Presentation A 30‐year‐old man underwent retroperitoneal tumor resection and was diagnosed
Hiraku Yamamoto, Isao Hara, Satoshi Muraoka, Takahito Wakaymiya, Shimpei Yamashita, Yasuo Kohjimoto   +5 more
wiley   +1 more source