Results 151 to 160 of about 94,427 (317)
TET family proteins play a critical role in DNA demethylation, and their mutations and dysregulation contribute to the onset of multiple diseases. With a deeper understanding of the molecular mechanisms of TET involvement in disease, drug therapy targeting TET proteins shows great potential, which provides insights into new therapeutic strategies ...
Junzhi Liang+12 more
wiley +1 more source
ABSTRACT Objectives Despite improved long‐term prognosis, childhood cancer survivors often experience many long‐term complications, which severely affect their quality of life. The aim of this scoping review is to summarize empirical evidence on suicidal ideation, attempt and mortality in childhood cancer survivors in order to contribute to the further
Eva De Clercq+2 more
wiley +1 more source
Canine ovarian gonadoblastoma (GB) (with SALL4, OCT‐4, E‐cadherin, α‐inhibin, AE1/AE3, and WT‐1 immunoreactivity) and two mammary carcinomas have been described in a genetically normal female Spitz. The scarcity of GB in dogs, aberrant WT‐1 expression in the germ cell component, and lack of the AMELY gene are the most remarkable features of the present
Diba Golchin+4 more
wiley +1 more source
Phenotype and gene signature of testicular tumors in 129.MOLF‐Chr19 mice resemble human teratomas
Abstract Background Testicular germ cell tumor (TGCT) is the most common type of tumor in young men. Type II germ cell tumors including postpubertal‐type teratomas are derived from the germ cell neoplasia in situ (GCNIS), whereas prepubertal‐type teratomas arise independently of the GCNIS.
Fabian A. Gayer+4 more
wiley +1 more source
Evaluation of commonly used ectoderm markers in iPSC trilineage differentiation. [PDF]
Patient-derived induced pluripotent stem cells (iPSCs) have become a promising resource for exploring genetics of complex diseases, discovering new drugs, and advancing regenerative medicine.
Iacovino, Michelina+11 more
core
Clinical Value of Prolan a Determinations in Teratoma Testis [PDF]
Max Cutler, S. E. Owen
openalex +1 more source
Objective To analyse a comparatively large cohort of patients who underwent robot‐assisted retroperitoneal lymph node dissection (R‐RPLND) in a single centre, assessing the peri‐operative and oncological safety of this procedure compared to that in a matched‐pair cohort of patients who underwent open retroperitoneal lymph node dissection (O‐RPLND ...
Pailin Pongratanakul+6 more
wiley +1 more source
Extra-gonadal germ cell tumour – what about the testis! [PDF]
Extra-gonadal germ cell tumours (EGGCT) are rare. Therefore further investigations of the testis is aimed at sourcing a possible primary origin of gonadal tumour. Over the years, various case series on EGGCT have been reported questioning its true nature
Christopher CKH,+5 more
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