TRIM28-Regulated Transposon Repression Is Required for Human Germline Competency and Not Primed or Naive Human Pluripotency. [PDF]
, 2018 Transition from primed to naive pluripotency is associated with dynamic changes in transposable element (TE) expression and demethylation of imprinting control regions (ICRs).
Chen, Pao-Yang +9 more
core +5 more sources
Dnd1-mediated epigenetic control of teratoma formation in mouse
Biology Open, 2018 Spontaneous testicular teratoma develops from primordial germ cells (PGCs) in embryos; however, the molecular mechanisms underlying teratoma formation are not fully understood. Mutation of the dead-end 1 (Dnd1) gene, which encodes an RNA-binding protein,
Wei Gu +5 more
doaj +1 more source
Extraordinary large primary retroperitoneal cystic teratoma: An extremely rare neoplasm
African Journal of Urology, 2012 Teratomas are the germ cell tumors which comprises of tissues from all the three germ cell layers. Primary retroperitoneal teratoma is a relatively rare tumor in adults. The primary retroperitoneal teratoma constitutes 6–11% of the retroperitoneal tumors.
P.K. Rai, B. Nayak, A. Seth
doaj +1 more source
Cancer-associated TERT promoter mutations abrogate telomerase silencing. [PDF]
, 2015 Mutations in the human telomerase reverse transcriptase (TERT) promoter are the most frequent non-coding mutations in cancer, but their molecular mechanism in tumorigenesis has not been established.
Boyle, John +5 more
core +1 more source
Intrapericardial immature teratoma with pericardial effusion in a 4-month-old boy
Journal of Pediatric Surgery Case Reports, 2020 Intrapericardial teratoma is an extremely rare mediastinal teratoma that arises at the junction of the ascending aorta and right atrial appendage. The teratoma is often complicated by massive pericardial effusion that compresses the heart and lungs ...
Teizaburo Mori +14 more
doaj +1 more source
Standardization of the teratoma assay for analysis of pluripotency of human ES cells and biosafety of their differentiated progeny. [PDF]
PLoS ONE, 2012 Teratoma tumor formation is an essential criterion in determining the pluripotency of human pluripotent stem cells. However, currently there is no consistent protocol for assessment of teratoma forming ability.
Michal Gropp +10 more
doaj +1 more source
Postgraduate Medical Journal, 1983 SummaryIntrarenal teratomas are extremely rare. A case of intrarenal teratoma in an adult is reported.
openaire +2 more sources
Ovarian teratoma in the mare: a review and two cases [PDF]
, 2010 A 4-year-old Belgian Warmblood mare suffering from pelvic flexure impaction was diagnosed with a teratoma of the left ovary. The enlarged ovary was identified several days after treatment of the impaction.
de Kruif, Aart +10 more
core
FDG‐PET Associations With Disease Severity and Outcomes in NMDA‐Receptor IgG Autoimmune Encephalitis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Patients with N‐methyl‐D‐aspartate (NMDA) receptor‐immunoglobulin G (IgG) autoimmune encephalitis (NMDAR‐IgG AE) demonstrate occipital lobe hypometabolism on baseline brain fluorodeoxyglucose‐positron emission tomography (bFDG‐PET).
Jonathan K. Lee +7 more
wiley +1 more source
Sacrococcygeal teratoma in one twin: a case report and literature review
BMC Pregnancy and Childbirth, 2020 Background Sacrococcygeal teratoma is one of the most common congenital tumors in newborns and infancy. The incidence is 1 per 20,000–40,000 live births.
Qing Hu +5 more
doaj +1 more source