Results 61 to 70 of about 95,175 (328)
Standardization of the teratoma assay for analysis of pluripotency of human ES cells and biosafety of their differentiated progeny. [PDF]
PLoS ONE, 2012 Teratoma tumor formation is an essential criterion in determining the pluripotency of human pluripotent stem cells. However, currently there is no consistent protocol for assessment of teratoma forming ability.
Michal Gropp +10 more
doaj +1 more source
Preventing Pluripotent Cell Teratoma in Regenerative Medicine Applied to Hematology Disorders
Stem Cells Translational Medicine, 2016 Iatrogenic tumorigenesis is a major limitation for the use of human induced pluripotent stem cells (hiPSCs) in hematology. The teratoma risk comes from the persistence of hiPSCs in differentiated cell populations. Our goal was to evaluate the best system
A. Bedel +10 more
semanticscholar +1 more source
Primate Primordial Germ Cells Acquire Transplantation Potential by Carnegie Stage 23. [PDF]
, 2017 Primordial germ cells (PGCs) are the earliest embryonic progenitors in the germline. Correct formation of PGCs is critical to reproductive health as an adult.
Chen, Di +7 more
core +5 more sources
Sacrococcygeal teratoma in one twin: a case report and literature review
BMC Pregnancy and Childbirth, 2020 Background Sacrococcygeal teratoma is one of the most common congenital tumors in newborns and infancy. The incidence is 1 per 20,000–40,000 live births.
Qing Hu +5 more
doaj +1 more source
Taiwanese Journal of Obstetrics & Gynecology, 2017 Objective: Benign mature teratoma during pregnancy is common, mostly discovered incidentally by antenatal sonography. However, repeated pregnancy coincident with ovarian mature teratoma is rarely reported.
Liang-Hsuan Chen +5 more
doaj +1 more source
Ovarian teratoma in the mare: a review and two cases [PDF]
, 2010 A 4-year-old Belgian Warmblood mare suffering from pelvic flexure impaction was diagnosed with a teratoma of the left ovary. The enlarged ovary was identified several days after treatment of the impaction.
de Kruif, Aart +10 more
core
Cell Death and Disease, 2016 Pluripotency makes human pluripotent stem cells (hPSCs) promising for regenerative medicine, but the teratoma formation has been considered to be a major obstacle for their clinical applications.
Hongling Li +14 more
semanticscholar +1 more source
Advanced Functional Materials, EarlyView.Oct4‐nanoscript, a biomimetic nanoparticle‐based artificial transcription factor, precisely regulates cellular rejuvenation by activating Oct4 target genes, restoring epigenetic marks, and reducing DNA damage. In a progeria model, it effectively rescued aging‐associated pathologies and extended lifespan.
Hongwon Kim +8 more
wiley +1 more source