Results 81 to 90 of about 43,363 (192)

Evaluation of commonly used ectoderm markers in iPSC trilineage differentiation. [PDF]

, 2019
Patient-derived induced pluripotent stem cells (iPSCs) have become a promising resource for exploring genetics of complex diseases, discovering new drugs, and advancing regenerative medicine.
Iacovino, Michelina, Iribarren, Carlos, Krauss, Ronald M, Kuang, Yu-Lin, Mattis, Aras N, Medina, Marisa W, Munoz, Antonio, Nalula, Gilbert, Sanchez, Gabriela, Sanghez, Valentina, Santostefano, Katherine E, Terada, Naohiro   +11 more
core  

Malignant ovarian germ cell tumors in pediatric patients: The AIEOP (Associazione Italiana Ematologia Oncologia Pediatrica) study [PDF]

, 2017
Objective: Malignant ovarian germ cell tumors (MOGCT) carry an excellent prognosis, and the treatment aims to achieve results with the least possible treatment-related morbidity. The aim of this study was to assess the outcomes of pediatric patients with
Amsalem, Baranzelli, Billmire, Billmire, Billmire, Frazier, Gershenson, Gershenson, Gobel, Grimison, Hanna, Kaplan, Kollmansberger, Lhommé, Lo Curto, Lopes, Madenci, Mangili, Mangili, Mangili, Mann, Matei, Meisel, Murray, Olson, Palenzuela, Park, Parkinson, Pashankar, Patterson, Pectasides, Rescorla, Robison, Rogers, Schemper, Schenider, Solheim, Stoneham, Travis, Vicus, Zagamè   +40 more
core   +1 more source

In‐Tumor CRISPR‐Cas9 Knockout Screening and Novel Therapy Development for Malignant Transformation of Ovarian Teratoma

Cancer Science, EarlyView.
We conducted an in vivo genome‐wide CRISPR‐Cas9 knockout screen using MTMCT‐derived cells to identify genes essential for tumor growth. SOD1 emerged as a key therapeutic target, and its inhibition suppressed tumor proliferation by disrupting redox homeostasis, both in vitro and in PDX models. ABSTRACT Malignant transformation of mature cystic teratoma (
Satoshi Tamauchi, Kosuke Yoshida, Wang Xinyuan, Atsushi Nakagawa, Akira Yokoi, Nobuhisa Yoshikawa, Kaoru Niimi, Yusuke Yamamoto, Hiroaki Kajiyama   +8 more
wiley   +1 more source

Malignant transformation in mature cystic teratoma of ovary: Series of 4 cases

Journal of Pathology of Nepal
Mature cystic teratoma is the most common benign ovarian tumour of germ cell origin. Malignant transformation is rare in mature cystic teratoma. Here we present a series of 4 cases showing malignant transformation in the form of squamous cell carcinoma ...
Aruna Gupta, Nandita Katoch, Garima Shah, Vikas Gupta, Nikhil Verma   +4 more
doaj   +1 more source

Extra-gonadal germ cell tumour – what about the testis! [PDF]

, 2011
Extra-gonadal germ cell tumours (EGGCT) are rare. Therefore further investigations of the testis is aimed at sourcing a possible primary origin of gonadal tumour. Over the years, various case series on EGGCT have been reported questioning its true nature
Christopher CKH,, Goh EH,, Johann FK,, Praveen S,, Razman J,, Zulkifli MZ,   +5 more
core  

Detection of the Heterozygous Recurrent MAX p.(Arg60Gln) Variant in Two Females Confirms and Expands the Phenotypic Spectrum of Polydactyly–Macrocephaly Syndrome

Clinical Genetics, EarlyView.
We identified a recurrent heterozygous MAX c.179G>A:p.Arg60Gln variant in two unrelated females affected with the emerging phenotypes of MAX‐associated polydactyly‐macrocephaly syndrome. We propose that genitourinary abnormalities, including Mayer–Rokitanski–Kuster–Hauser syndrome in one individual, are an expansion of the known phenotypes associated ...
Iftekhar A. Showpnil, Neta Feinstein‐Goren, Lior Greenbaum, Ortal Barel, Daniel C. Koboldt, Samantha A. Brugmann, Kathryn Nicole Weaver, Anne Slavotinek, Ben Pode‐Shakked, Rolf W. Stottmann   +9 more
wiley   +1 more source

Original Articles Preoperative Hematological Parameters for Predicting Ovarian Torsion in Patients with Mature Cystic Teratoma

, 2021
Jisun Lee, Jin‐Young Park, Hyun Jung Lee, Mi Ju Kim, Yoon Hee Lee, Gun Oh Chong, Dae Gy Hong, Taek Hoo Lee   +7 more
openalex   +2 more sources

Intermediate Immature Teratoma [PDF]

, 2020
National Cancer Institute
openalex   +1 more source

Total en bloc spondylectomy in testicular immature teratoma: Long‐term survival amidst vertebral metastasis escalated by growing teratoma syndrome

IJU Case Reports
Introduction We present a rare case of long‐term survival following metastasectomy for lumbar metastasis with growing teratoma syndrome. Case presentation An 18‐year‐old man presented with left scrotal mass and lumbago.
Masahiro Tamaki, Kouhei Maruno, Tatsuya Hazama, Toshifumi Takahashi, Yuya Yamada, Masakazu Nakashima, Kazuro Kikkawa, Noriyuki Ito   +7 more
doaj   +1 more source

Struma Ovarii Associated with Pseudo- Meigs’Syndrome [PDF]

, 2012
Struma ovarii is a specialized ovarian teratoma composed predominantly of mature thyroid tissue. It is associated with pleural effusion and ascites (Pseudo-Meigs’ syndrome) in 5% of cases.
Gangane, NM, Gulhane, SR, Sinha, RT
core   +1 more source