Results 231 to 240 of about 16,466 (254)
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Tissue distribution of terbinafine in rats
Journal of Pharmaceutical Sciences, 2001Terbinafine is an allylamine antifungal agent that is highly lipophilic and keratophilic. The aim of this study was to investigate terbinafine distribution in peripheral and visceral tissues after intravenous administration to rats. Terbinafine, 6 mg/kg, was administered to 33 male Sprague-Dawley rats via a jugular vein cannula over 30 s.
Mahboubeh Hosseini-Yeganeh +1 more
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Management of onychomycosis with oral terbinafine
Journal of the American Academy of Dermatology, 1990The safety and efficacy of oral terbinafine in the treatment of finger onychomycosis caused by Trichophyton rubrum were evaluated in an open study including 11 patients. Treatment consisted of 125 mg of terbinafine given twice daily for 6 months or until the infection cleared.
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Mupirocin vs terbinafine in impetigo
The Indian Journal of Pediatrics, 2002Terbinafine is an antifungal drug known to have also antibacterial activity against certain Gram-positive and Gram-negative bacteria. It seems that antibacterial and antifungal activity of terbinafine may have an advantage in the treatment of mixed fungal and bacterial superficial skin infections.
Ahmet Derya Aysev +2 more
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Terbinafine-associated hepatic injury
Journal of Hepatology, 1994We describe two cases of terbinafine-associated hepatic injury, in which a mixed cholestatic-hepatocellular type of hepatitis was present. In both cases extrahepatic cholestasis and viral hepatitis were excluded and involvement of other drugs was unlikely.
Bruno H. Stricker +3 more
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Interaction between Terbinafine and Warfarin
Dermatology, 1998A 71-year-old woman presented with gastrointestinal bleeding. She had been stabilized on warfarin for the previous few months. Terbinafine had been started 32 days prior to this episode for the treatment of onychomycosis. The patient had been on cimetidine for the previous 2 years and on other medications for the last 10 years. At the time of admission
G.S. Ross, Aditya K. Gupta
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Therapeutic Review: Terbinafine
Journal of Exotic Pet Medicine, 2012al, U ard V Terbinafine is a synthetic allylamine antifungal used commonly in both human and veterinary medicine. Terbinafine inhibits squalene epoxidase, a key enzyme in ergosterol biosynthesis,1-4 thereby decreasing ergosterol synthesis and causing toxic levels of squalene to accumulate in the fungal cell.
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Oral terbinafine and erythema multiforme
Clinical and Experimental Dermatology, 1995Two patients developed classical erythema multiforme while taking oral terbinafine. A case of Stevens-Johnson syndrome occurring after terbinafine therapy has recently been described, but there have been no published reports of an association with erythema multiforme until now.
Dowling D. Munro, P. Todd, S.M. Halpern
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Preclinical evaluation of terbinafine in vivo
Clinical and Experimental Dermatology, 1989The fungicidal activity of terbinafine which has been demonstrated in vitro for several strains of dermatophyte, filamentous and dimorphic fungi, has been demonstrated in vivo in model systems for dermatophytoses. This activity is accompanied by a fast onset of action which leads to superior antifungal efficacy when compared with fungistatic drugs.
H. Mieth, G. Petranyi
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Erroneous substitution of terbinafine for lamotrigine
Neurology, 1997Inadvertent substitutions of one pharmaceutical agent for another are frequently reported for many medications, including antiepileptic drugs. Occasionally, serious adverse effects have resulted from such dispensing errors. Multiple causes exist for these mistakes: two medications can have similar generic or brand names, tablets made by one ...
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