Results 161 to 170 of about 11,293 (309)

NPM1 Mediates mRNA Sorting into Extracellular Vesicles via Specific RNA Motif Binding and Phase Separation

Advanced Science, EarlyView.
NPM1 selectively sorts specific mRNAs into extracellular vesicles (EVs) by recognizing RNA motifs and forming phase‐separated condensates. These mRNA cargos—including EGFR—are then loaded via multivesicular bodies. This active sorting pathway, validated in EVs derived from both lung cancer cells and patient serum, reveals a specific mechanism for ...
Kaixiang Zhang, Gaoge Sun, Xiangzheng Liu, Shuai Zuo, Pengyuan Wang, Boxiao Zhan, Zhi John Lu, Hang Yin, Ying Zhang   +8 more
wiley   +1 more source

Is Terbium-161 the Next Lutetium-177? A New Era for Theranostics on the Horizon. [PDF]

Indian J Nucl Med
Sharma P.
europepmc   +1 more source

Timing Mechanotransduction: Mechanically Dynamic Biomaterials Reveal the Temporal Hierarchy of YAP/TAZ Control Nodes

Advanced Science, EarlyView.
This work develops dynamically softening polyacrylamide hydrogels for time‐resolved imaging during continuous mechanical transitions. The study revealed that mechanotransduction is biphasic; YAP/TAZ inactivation is driven by early loss of the nucleocytoskeletal continuum connecting subnuclear adhesions, F‐actin, and the nuclear envelope, coupled with ...
Alessandro Gandin, Giada Vanni, Veronica Torresan, Margherita Pelosin, Rebecca Busetto, Anna Citron, Ambela Suli, Paolo Contessotto, Carlo Albanese, Francesca Zanconato, Tito Panciera, Stefano Piccolo, Giovanna Brusatin   +12 more
wiley   +1 more source

Recommendations on the Clinical Application and Future Potential of α-Particle Therapy: A Comprehensive Review of the Results from the SECURE Project. [PDF]

Pharmaceuticals (Basel)
Di Iorio V, Sarnelli A, Boschi S, Sansovini M, Genovese RM, Stefanescu C, Ghizdovat V, Jalloul W, Young J, Sosabowski J, Kolenc P, Roberts R, With G, Visvikis D, Mikolajczak R.   +14 more
europepmc   +1 more source

Anilidophosphine ligand supported praseodymium and terbium phosphaethynolate complexes: Synthesis, characterization, and DFT calculations

, 2023
Chi, Xiao-Wang, Bin Li, Kang Liu, Qun‐Yan Wu, Kong‐Qiu Hu, Lei Mei, Ru’an Chi, Jipan Yu   +7 more
openalex   +1 more source

CRP Deficiency Rescues Periodontitis‐Induced Hippocampal Neurogenesis Impairment by Suppressing OPC‐Derived BMP4 Signaling in Rats

Advanced Science, EarlyView.
Chronic periodontitis elevates circulating CRP, which enters the hippocampus to upregulate BMP4 in oligodendrocyte precursor cells (OPCs), thereby impairing neurogenesis and inducing anxiety/depression‐like behaviors in rats. Counteracting this pathway, CRP deficiency helps confer functional resilience to OPCs.
Lingjie Li, Ping Deng, Siyu Hou, Xianbo Xia, Wei Zhao, Xingyu Zhu, Yang Zhang, Chao Wang, Ling Xu, Jinlin Song   +9 more
wiley   +1 more source

Visualization of Endosomal Escape of Intracellularly Delivered Protein With Unexpected Photochemical Internalization of Trypan Blue

Advanced Science, EarlyView.
TB, a conventional cell viability dye, acts as both a fluorescence modulator (quenching GFP fluorescence upon protein binding and recovering it upon release) and a photosensitizer that triggers endosomal escape via photochemical internalization (PCI) under 590 nm light.
Zhongqi Yao, Zhan Shi, Peng Hu, Changping Wang, Hui Wang   +4 more
wiley   +1 more source

Speciation and Luminescence of a Binuclear Lanthanide Complex Bearing an Aminophenolate Chromophore. [PDF]

Chemistry
Nielsen VRM, Simms CH, Kovacs D, Allen MF, Langton MJ, Faulkner S, Sørensen TJ.   +6 more
europepmc   +1 more source

Synthesis of Redox-Active Terbium(III)-Based Metal–OrganicFramework Crystals and Visual Fluorescence Sensing for VanillylmandelicAcid

Miao-Miao Wang (2064772), Huan Zhang (220065), Jun-Jie Hu (8446557), Yan Peng (104995), Sui-Jun Liu (1605664), He-Rui Wen (542152)   +5 more
openalex   +1 more source

Search for magnetoelastic spin liquid state in terbium gallium garnet(Tb3Ga5O12).

, 2016
R. Wawrzyńczak, Martin Boehm, Fennell Tom, M. Kenzelmann, Mutka Hannu, Nilsen Goran, Jacques Ollivier   +6 more
openalex   +1 more source