Results 81 to 90 of about 17,280 (228)

Co‐Occurrence of Endogenous and Exogenous Cushing's Syndromes: Does “Double Cushing Syndrome” Really Exist? A Case Report

Clinical Case Reports, Volume 13, Issue 11, November 2025.
ABSTRACT Double Cushing syndrome exists: exogenous steroid use can mask concurrent adrenal hypercortisolism. When symptoms persist and cortisol remains high after tapering or stopping prescribed glucocorticoids, an endogenous source is likely. Early recognition with ACTH testing, dexamethasone suppression, and adrenal imaging reduces misdiagnosis ...
Reza Amani‐Beni, Atiyeh Karimi Shervedani, Bahar Darouei, Matin Noroozi, Maryam Heidarpour   +4 more
wiley   +1 more source

Strontium ranelate effect on bone mineral density is modified by previous bisphosphonate treatment [PDF]

, 2014
The aim of this study was to evaluate the effect of strontium ranelate (SrR) on bone mineral density (BMD) and boneturnover markers after 1 year of treatment.
Brance, María Lorena, Brun, Lucas Ricardo Martín, Costanzo, Paulo R, Galich, Ana M., Grupo Argentino de Estudio del Ranelato de Estroncio, Larroudé, Maria S., Maffei, Laura, Moggia, Maria S., Premrou, Valeria, Rey, Paula, Salerni, Helena, Sarli, Marcelo A, Sánchez, Ariel, Vega, Eduardo   +13 more
core   +1 more source

Circadian Rhythm: Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 6, Issue 11, November 2025.
This review offers a comprehensive overview of the mechanisms by which circadian rhythms modulate tissue homeostasis, alongside the associations between circadian disturbances and circadian rhythm‐related diseases. Furthermore, we offer insights into circadian rhythm‐regulating therapies, which may contribute to the development of novel strategies for ...
Kangkang Zha, Bobin Mi, Yuan Xiong, Shuyan Wu, Li Lu, Shengming Zhang, Xuan Lu, Hei Chung Mak, Jianping Huang, Adriana C. Panayi, Samuel Knoedler, Lili Chen, Guohui Liu, Sien Lin   +13 more
wiley   +1 more source

Teriparatid [PDF]

pharma-kritik, 2005
Dieses Medikament, abgeleitet vom menschlichen Parathormon, reduziert bei Frauen mit Osteoporose-bedingten Wirbelfrakturen das Risiko von weiteren Wirbelfrakturen.
openaire   +1 more source

Mineral maturity and crystallinity index are distinct characteristics of bone mineral [PDF]

, 2010
The purpose of this study was to test the hypothesis that mineral maturity and crystallinity index are two different characteristics of bone mineral. To this end, Fourier transform infrared microspectroscopy (FTIRM) was used.
A Boskey, A Carden, A Carden, A Gee, A Shemesh, AB Barry, AC Ferrari, AL Boskey, AL Boskey, AL Boskey, AS Posner, B Giri, C Jager, C Rey, C Rey, C Rey, C Rey, CH Turner, CH Turner, CH Turner, Christian Rey, CP Tarnowski, D Chachra, D Faibish, Delphine Farlay, E Durchschlag, E Fitzer EG, E Pucéat, EP Paschalis, EP Paschalis, EP Paschalis, EP Paschalis, G Boivin, Georges Boivin, Gérard Panczer, J Green, JD Termine, JS Yerramshetty, JW Ager, KL Dziak, L Nasdala, LM Miller, LM Miller, LM Miller, MD Grynpas, MD Morris, MG Glimcher, N Pleshko, NP Camacho, O Akkus, O Akkus, P Fratzl, P Fratzl, PD Frazier, Pierre D. Delmas, RG Hanschin, RY Huang, RZ Legeros, S Bang, S Bohic, S Cazalbou, S Tadano, SJ Gadaleta, WJ Landis, Y Li   +64 more
core   +3 more sources

Advances in Molecularly Imprinted Polymers for Bone Biomarker Detection and Therapeutic Applications

ChemistryOpen, Volume 14, Issue 11, November 2025.
This review highlights the emerging applications of molecularly imprinted polymers (MIPs) in bone regeneration and diagnosis. MIPs facilitate osteogenic treatments by guiding stem cell differentiation and delivering bioactive molecules and enable precise detection of bone turnover biomarkers via MIP‐based sensors, offering promising strategies for next‐
Ren Yang, Xiaohan Ma, Mingcheng Xuan, Yingqi Ma, Jiexian Ding, David Y. S. Chau, Jonathan C. Knowles, Feng Peng, Alessandro Poma   +8 more
wiley   +1 more source

Efficacy and safety of denosumab and teriparatide versus oral bisphosphonates to treat postmenopausal osteoporosis: a systematic review and meta-analysis

Frontiers in Endocrinology
Study DesignA systematic review and Meta-analysisObjectiveTo compare the efficacy and safety of denosumab and teriparatide versus oral bisphosphonates to treat postmenopausal osteoporosis.Summary of Background DataWhile bisphosphonates have historically ...
Jia Yang, Xiaobo Guo, Zhongning Cui, Huikang Guo, Jia-Nan Dong   +4 more
doaj   +1 more source

Effects of abaloparatide and teriparatide on bone resorption and bone formation in female mice

Bone Reports, 2020
Intermittent administration of PTH type 1 receptor (PTH1R) agonists increases bone remodeling, with greater stimulation of bone formation relative to bone resorption causing net gains in bone mass. This pharmacodynamic feature underlies the bone-building
Heike Arlt, Tara Mullarkey, Dorothy Hu, Roland Baron, Michael S. Ominsky, Bruce Mitlak, Beate Lanske, Tatiana Besschetnova   +7 more
doaj   +1 more source

Impact of bisphosphonate wash-out prior to teriparatide therapy in clinical practice [PDF]

, 2018
Concurrent use of bisphosphonate therapy reduces the anabolic effect of teriparatide. Consequently, in clinical practice bisphosphonates are discontinued and teriparatide therapy held for a few months to allow bone turnover to increase.
Keel, Christina, Kraenzlin, Claude, Kraenzlin, Marius, Meier, Christian, Müller, Beat   +4 more
core  

Salvianolic Acid A Mitigates Osteoporotic Bone Loss by Repressing Reactive Oxygen Species via the Nrf2–HO‐1 Pathway

Phytotherapy Research, Volume 39, Issue 11, Page 4977-4990, November 2025.
ABSTRACT Osteoporosis, characterized by osteoclastic bone resorption, has been the focus of research. Studies implicate that reactive oxygen species (ROS) accumulate intracellularly during osteoclastogenesis. Salvianolic acid A (SAA), a compound derived from Salvia miltiorrhiza, has been widely used to treat cardiovascular and cerebrovascular disorders,
Hao Qiu, Chenhui Cai, Ying Zhang, Sizhen Yang, Xu Hu, Tongwei Chu   +5 more
wiley   +1 more source